Phosphatases in Cell Metabolism and Signal Transduction: Structure, Function and Mechanism of Action (Molecular Biology Intelligence Unit)

A summary of the mechanisms for phosphate monoester hydrolysis, first examining the manners in which this hydrolysis is catalyzed by simple model complexes. Subsequently, the six well-characterized classes of enzymes which catalyze phosphate monoester hydrolysis phosphatases are examined in detail: serine/threonine phosphatases, purple acid phosphatases, low molecular weight acid phosphatases, and high molecular weight phosphatases. The discussions focus on the chemistry of these enzymes on a molecular level, i.e., their structure, function, and mechanism of action. Annotation copyright Book News, Inc. Portland, Or.