With a focus on real-world applications and a conversational tone, this laboratory manual contains experiments written specifically to correspond with Chemistry: A Molecular Approach, Third Edition by Nivaldo J. Tro. Each experiment covers one or more topics discussed within a chapter of the textbook, with the dual goal of 1) helping students understand the underlying concepts covered in the lecture course, and 2) presenting this material in a way that is interesting and exciting. This manual contains twenty-eight experiments with a focus on real world applications. Each experiment contains a set of pre-laboratory questions, an introduction, a step-by-step procedure (including safety information), and a report section featuring post-laboratory questions. Additional features include a section on laboratory safety rules, an overview on general techniques and equipment, as well as a detailed tutorial on graphing data in Excel.

Chemistry: A Molecular Approach

Science & Math

Tro, Nivaldo J.

Vincent, John B.

Livingston, Erica

Chemistry

Pearson College Div

Chromium exists in nature as complexes of two stable oxidation states – trivalent chromium(III) and hexavalent chromium(VI).  Although trivalent chromium is required in trace amounts for sugar and lipid metabolism in humans and its deficiency may cause a disease called chromium deficiency; hexavalent chromium is toxic and carcinogenic. As chromium compounds were used in dyes and paints and the tanning of leather, these compounds are often found in soil and groundwater at abandoned industrial sites, now needing environmental cleanup and remediation. The Bioinorganic Chemistry of Chromium: From Biochemistry to Environmental Toxicology takes a critical look at what the biochemical data indicate about chromium's role in the body and the biological mechanisms of its  toxicology. Topics covered include:  What do we know about the biochemical roles and mechanisms of chromium? Is chromium an essential element in the mammalian diet? Is chromium(III) effective as a nutraceutical, a therapeutic agent, and as a supplement in  animal feed? What is the biochemistry behind the toxicology of chromium(III) and chromium(VI):the mechanisms of metabolism, genetic and epigenetic effects, and disruption of cell signalling? What are the current chromium(VI) policies and positions from regulatory agencies?  The Bioinorganic Chemistry of Chromium: From Biochemistry to Environmental Toxicology is an important contribution to the bioinorganic and trace element biochemical fields which will find a place on the bookshelves of bioinorganic chemists, biochemists, inorganic chemists,  toxicologists, nutritionists and regulatory affairs professionals.

The Bioinorganic Chemistry of Chromium

Biological Sciences

wiley

A summary of the mechanisms for phosphate monoester hydrolysis, first examining the manners in which this hydrolysis is catalyzed by simple model complexes. Subsequently, the six well-characterized classes of enzymes which catalyze phosphate monoester hydrolysis phosphatases are examined in detail: serine/threonine phosphatases, purple acid phosphatases, low molecular weight acid phosphatases, and high molecular weight phosphatases. The discussions focus on the chemistry of these enzymes on a molecular level, i.e., their structure, function, and mechanism of action. Annotation copyright Book News, Inc. Portland, Or.

Phosphatases in Cell Metabolism and Signal Transduction: Structure, Function and Mechanism of Action (Molecular Biology Intelligence Unit)

Crowder, Michael W.

R G Landes Co

This book is about the chemistry of phosphate monoester hydrolysis catalyzed by enzymes called phosphatases, focusing on their chemistry at a molecular level, i.e. their structure, function, and mechanism of action. At present, six classes of phosphatase are well characterized: (i) alkaline phosphatases, (ii) purple acid phosphatases, (iii) high molecular weight acid phosphatases, (iv) low molecular weight acid phosphatases, (v) phosphotyrosine phosphatases, and (vi) serine/threonine phosphatases. This book presents a comprehensive overview of phosphatases, comparing and contrasting Nature's different solutions to the problem of phosphate monoester hydrolysis. This is the first thorough survey and comparison of these different types of phosphatases. It focuses on chemistry, not biology.

Springer

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