This volume addresses some facets of the adverse actions of chemical agents on the central and peripheral nervous systems in developing and mature states. Some of the effects of these chemicals are short-lasting and rapidly reversible; others, especially those that cause structural damage to the nervous system, may result in permanent damage to the organism. The nervous system has several levels of vulnerability to toxic substances. Some substances perturb ion channels or synaptic mechanisms required for the orderly transfer of electrochemical information within the nervous system. Others disrupt sites required for the maintenance of cellular integrity, and these variably result in degenerative responses of neurons and myelinating cells. Further sites of vulnerability include the delicate neural vasculature and neurohumeral mechanisms responsible for physiological homeostasis. The science of neurotoxicology inevitably is a multidisciplinary endeavor, with contributions from biochemistry, physiology, morphology and behavior, to name a few. The challenge is to apply appropriate techniques to investigate neurotoxic phenomena. The first logical step in this analysis is to determine from the point of view of the nervous system the nature of the exposure. Is the chemical a single or multiple entity; is it metabolized; how does it gain access to neural tissue? Once these factors are understood, changes induced by the exposure can be described at various levels from the biochemical to the behavioral.

Recent Advances in Nervous System Toxicology (Nato Science Series A:)

Manzo, Luigi

Galli, Corrado L.

Health, Fitness & Dieting

New York, New York, U.S.A.: Plenum Pub Corp

Many chemical compounds present in workplace settings can produce a number of impairments in the human nervous system. As the situations in which neurotoxic agents have been recognized in exposed workers has grown, so has the importance of occupational neurotoxicology as a specialty. Addressing some of the most vital concerns in the field, Occupational Neurotoxicology discusses: 
<li>Neurotoxic agents commonly encountered in the workplace 
</li>
<li>Signs and symptoms of neurotoxicity and of the factors affecting neurotoxic effects 
</li>
<li>Biological monitoring and the use of biomarkers 
</li>
<li>Epidemiological methods and clinical approaches to occupational neurotoxicology 
</li>
<li>The analysis of behavioral, electrophysiological, and imaging techniques in the diagnosis of neurotoxicity 
</li>
<li>Occupational neurotoxicity in developing countries 
</li>
<li>The evaluation and management of occupational illnesses due to neurotoxicity Occupational Neurotoxicology concisely covers important facts on the adverse effects of chemical, biological, and physical agents that can impair or alter the structure of the nervous system. Professionals and researchers in the fields of occupational medicine, toxicology, epidemiology, neurology, industrial hygiene, and psychology will all find relevant information on the health problems that can occur from exposure to neurotoxicants.</li>

Occupational Neurotoxicology

Science & Math

Costa, Lucio G.

Biological Sciences

CRC-Press

Il dizionario degli alcolici

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Il libro dei cocktails internazionali IBA. Un viaggio attraverso 77 cocktails mondiali che ogni barman dovrebbe conoscere

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