A first-person account of a family's struggle with autism follows the author as he cares for his older brother, undiagnosed for fifty years, and discovers the illness in his own son years later

Without Reason: A Family Copes With 2 Generations of Autism

Health, Fitness & Dieting

Hart, Charles

Psychology & Counseling

Harpercollins

Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. 
This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large―indeed, anyone who touches this critical sphere of global impact―in and around academia and the biotechnology/pharmaceutical industry. Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters

Managing the Drug Discovery Process: Insights and advice for students, educators, and practitioners

Medical Books

MILLER, SUSAN

Moos, Walter

Munk, Stephen

Munk, Barbara

Spellmeyer, David

Pharmacology

Woodhead Publishing

Without Reason is Charles Hart's deeply personal, authoritative first-person probe of autism and its effects on his family. He takes us through his childhood with an autistic brother who needed constant care, to his scholarship education at Harvard, his own family of better circumstance, and the autism of his son Ted. Armed with the available knowledge about autism - one of the most enigmatic of all known disorders - he has set out to improve the quality of life for his brother, his son, and other persons with autism and their families. Through his work with the Autism Society of America and the Association for Retarded Citizens, he has accomplished this goal by providing new opportunities for learning and growth for his brother Sumner, Ted, and other people with disabilities. This is a story of one family's triumph, its victory over a social system that rarely allows for special needs, and of personal reaction with a mysterious and frustrating disorder of the mind. Charles Hart understands autism as few others can and thus offers the reader an intimate view of a family's struggle, not for a cure but for understanding and accommodation of people disabled by autism.

Without Reason: A Family Copes With Two Generations of Autism

Signet

Despite the tremendous need for parents of autistic children to learn as much as they can about treatments, life choices, and possible cures, there has never been a broad subject survey or a complete examination of the anecdotal evidence until now. Includes the success rate of the best-known treatments and more.

A Parent'S Guide To Autism: A Parents Guide To Autism

Parenting & Relationships

Parenting

GALLERY BOOKS

A Manual of Bible History

History

Wentworth Press

This scarce antiquarian book is a facsimile reprint of the original. Due to its age, it may contain imperfections such as marks, notations, marginalia and flawed pages. Because we believe this work is culturally important, we have made it available as part of our commitment for protecting, preserving, and promoting the world's literature in affordable, high quality, modern editions that are true to the original work.

Sorcerer's Drum

Literature & Fiction

Evans, Daniel W.

Dramas & Plays

Kessinger Publishing

Following on the success of Goldpanning in the Cariboo, their first collaboration, Jim Lewis and Charles Hart now identify prominent gold-bearing creeks in southwestern British Columbia. The directions, maps, and first-hand advice included in this book are largely based on the diaries and research of a lifelong prospector. Jim Lewis has walked these creekbeds and studied their channel shifts, trusty gold pan in hand. Semi-retired and content with his "poke," Jim is a strong advocate of prospecting as a recreational activity for people of all ages. To introduce familes, hikers, and nature lovers to the glories of one of B.C.'s most colourful regions and encourage them to reap the fun and rewards that can come from a gold pan, Jim reveals information it has taken a life time to garner.

Goldpanning Southwest Bc & Vancouver Island: A Prospectors Treasure Trail to Creeks of Gold (Creeks of Gold Series)

Science & Math

Lewis,Jim

Nature & Ecology

Heritage House Pub Co Ltd

One of the major objectives of this book is to make Thomistic metaphysics an inquiry into the act of existing, the act of to be, exercised by all beings to some degree more understandable. The various problems of metaphysics and their solutions are presented in the simplest terms possible, with special emphasis on their significance for the contemporary mind.This is a reprint of the first edition.

Thomistic Metaphysics: An Inquiry into the Act of Existing (Scholastic Editions – Editiones Scholasticae)

Politics & Social Sciences

Philosophy

Editiones Scholasticae, Germany

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