Pharmaceutical Microbiology: Essentials for Quality Assurance and Quality Control presents that latest information on protecting pharmaceutical and healthcare products from spoilage by microorganisms, and protecting patients and consumers. With both sterile and non-sterile products, the effects can range from discoloration to the potential for fatality. The book provides an overview of the function of the pharmaceutical microbiologist and what they need to know, from regulatory filing and GMP, to laboratory design and management, and compendia tests and risk assessment tools and techniques. These key aspects are discussed through a series of dedicated chapters, with topics covering auditing, validation, data analysis, bioburden, toxins, microbial identification, culture media, and contamination control.

Pharmaceutical Microbiology: Essentials for Quality Assurance and Quality Control

Business & Money

Sandle PhD, Tim

Management & Leadership

Woodhead Publishing

The future market forces and environmental considerations in the passenger car and commercial vehicle sector mean more stringent engine downsizing is far more prevalent. Therefore, novel systems are required to provide boosting solutions including hybrid, electric-motor and exhaust waste energy recovery systems for high efficiency, response, reliability, durability and compactness. The current emission legislations and environmental trends for reducing CO2 and fuel consumption are the major market forces in the land and marine transport industries. The internal combustion engine is the key product and downsizing, efficiency and economy are the driving forces for development for both spark ignition (SI) and compression ignition (CI) engines in both markets. Future market forces and environmental considerations for transportation, specifically in the passenger car, commercial vehicle and the marine sectors mean more stringent engine downsizing.  This international conference is the latest in the highly successful and prestigious series held regularly since 1978. These proceedings from the Institution’s highly successful and prestigious series address current and novel aspects of turbocharging systems design, boosting solutions for engine downsizing and improvements in efficiency, and present the latest research and development in this growing and innovative area. Focuses on boosting solutions including hybrid, electric-motor and exhaust waste energy recovery systemsExplores the current need for high efficiency, reliability, durability and compactness in recovery systemsExamines what new systems developments are underway

11th International Conference on Turbochargers and Turbocharging: 13-14 May 2014

Engineering & Transportation

Automotive

Polymer Optical Fibres: Fibre Types, Materials, Fabrication, Characterization, and Applications explores polymer optical fibers, specifically their materials, fabrication, characterization, measurement techniques, and applications. Optical effects, including light propagation, degrading effects of attenuation, scattering, and dispersion, are explained. Other important parameters like mechanical strength, operating temperatures, and processability are also described. Polymer optical fibers (POF) have a number of advantages over glass fibers, such as low cost, flexibility, low weight, electromagnetic immunity, good bandwidth, simple installation, and mechanical stability. Provides systematic and comprehensive coverage of materials, fabrication, properties, measurement techniques, and applications of POFFocuses on industry needs in communication, illumination and sensors, the automotive industry, and medical and biotechnologyFeatures input from leading experts in POF technology, with experience spanning optoelectronics, polymer, and textilesExplains optical effects, including light propagation, degrading effects of attenuation, scattering, and dispersion

Polymer Optical Fibres: Fibre Types, Materials, Fabrication, Characterisation and Applications (Woodhead Publishing Series in Electronic and Optical Materials)

Science & Math

Physics

Materials Characterization Using Nondestructive Evaluation (NDE) Methods discusses NDT methods and how they are highly desirable for both long-term monitoring and short-term assessment of materials, providing crucial early warning that the fatigue life of a material has elapsed, thus helping to prevent service failures. Materials Characterization Using Nondestructive Evaluation (NDE) Methods gives an overview of established and new NDT techniques for the characterization of materials, with a focus on materials used in the automotive, aerospace, power plants, and infrastructure construction industries. Each chapter focuses on a different NDT technique and indicates the potential of the method by selected examples of applications. Methods covered include scanning and transmission electron microscopy, X-ray microtomography and diffraction, ultrasonic, electromagnetic, microwave, and hybrid techniques. The authors review both the determination of microstructure properties, including phase content and grain size, and the determination of mechanical properties, such as hardness, toughness, yield strength, texture, and residual stress.

Materials Characterization Using Nondestructive Evaluation (NDE) Methods (Woodhead Publishing Series in Electronic and Optical Materials)

Experiments, Instruments & Measurement

Stress Corrosion Cracking of Nickel Based Alloys in Water-Cooled Nuclear Reactors: The Coriou Effect presents the latest information on brittle failure of metals in corrosive chemical environments under the influence of tensile stresses.  Nickel alloys are more resistant to SCC as well as high temperatures and have been widely used in more challenging environments such as nuclear power plants. However, these alloys can suffer SCC under certain conditions, resulting in component failure. A key figure in understanding the mechanisms of SCC in nickel alloys in water-cooled nuclear reactors is Henri Coriou of the CEA, France’s leading center for nuclear research. This book assesses his work in the context of the latest research on SCC in nickel alloys in nuclear power plants.Up-to-date reviews of recent research findings from leading experts in the field Authoritative and comprehensively reviewed by the Working Party 4 on Nuclear CorrosionShowcases the excellent quality and technical accomplishments of Henri Coriou and CEA

Stress Corrosion Cracking of Nickel Based Alloys in Water-cooled Nuclear Reactors: The Coriou Effect (Volume 67) (European Federation of Corrosion (EFC) Series, Volume 67)

Engineering

Most books discuss general and broad topics regarding molecular imagings. However, Ultrasmall Lanthanide Oxide Nanoparticles for Biomedical Imaging and Therapy, will mainly focus on lanthanide oxide nanoparticles for molecular imaging and therapeutics. Multi-modal imaging capabilities will discussed, along with up-converting FI by using lanthanide oxide nanoparticles. The synthesis will cover polyol synthesis of lanthanide oxide nanoparticles, Surface coatings with biocompatible and hydrophilic ligands will be discussed and TEM images and dynamic light scattering (DLS) patterns will be provided. Various techniques which are generally used in analyzing the synthesized surface coated nanoparticles will be explored and this section will also cover FT, IR analysis, XRD analysis, SQUID analysis, cytotoxicity measurements and proton relaxivity measurements. In vivo MR images, CT images, fluorescence images will be provided and Therapeutic application of gadolinium oxide nanoparticles will be discussed. Finally, future perpectives will be discussed. That is, present status and future works needed for clinical applications of lanthanide oxide nanoparticles to molecular imagings will be discussed.

Ultrasmall Lanthanide Oxide Nanoparticles for Biomedical Imaging and Therapy (Woodhead Publishing Series in Biomaterial, 68)

Lee, Gang Ho

Kim, Jeong-Tae

Biological Sciences

Applied plant genomics and biotechnology reviews the recent advancements in the post-genomic era, discussing how different varieties respond to abiotic and biotic stresses, investigating epigenetic modifications and epigenetic memory through analysis of DNA methylation states, applicative uses of RNA silencing and RNA interference in plant physiology and in experimental transgenics, and plants modified to produce high-value pharmaceutical proteins. The book provides an overview of research advances in application of RNA silencing and RNA interference, through Virus-based transient gene expression systems, Virus induced gene complementation (VIGC), Virus induced gene silencing (Sir VIGS, Mr VIGS) Virus-based microRNA silencing (VbMS) and  Virus-based RNA mobility assays (VRMA); RNA based vaccines and expression of virus proteins or RNA, and virus-like particles in plants, the potential of virus vaccines and therapeutics, and exploring plants as factories for useful products and pharmaceuticals are topics wholly deepened. The book reviews and discuss Plant Functional Genomic studies discussing the technologies supporting the genetic improvement of plants and the production of plant varieties more resistant to biotic and abiotic stresses. Several important crops  are analysed providing a glimpse on the most up-to-date methods and topics of investigation. The book presents a review on current state of GMO,  the cisgenesis-derived plants and novel plant products devoid of transgene elements, discuss their regulation and the production of desired traits such as resistance to viruses and disease also in fruit trees and wood trees with long vegetative periods. Several chapters cover aspects of plant physiology  related to plant improvement: cytokinin metabolism and hormone signaling pathways are discussed in barley; PARP-domain proteins involved in Stress-Induced Morphogenetic Response, regulation of NAD signaling and ROS dependent synthesis of anthocyanins. Apple allergen isoforms and the various content in different varieties are discussed and approaches to reduce their presence. Euphorbiaceae, castor bean, cassava and Jathropa are discussed at genomic structure, their diseases and viruses, and methods of transformation. Rice genomics and agricultural traits are discussed, and biotechnology for engineering and improve rice varieties. Mango topics are presented with an overview of molecular methods for variety differentiation, and aspects of fruit improvement by traditional and biotechnology methods. Oilseed rape is presented, discussing the genetic diversity, quality traits, genetic maps, genomic selection  and comparative genomics for improvement of varieties. Tomato studies are presented, with an overview on the knowledge of the regulatory networks involved in flowering, methods applied to study the tomato genome-wide DNA methylation, its regulation by small RNAs, microRNA-dependent control of transcription factors expression, the development and ripening processes in tomato, genomic studies and fruit modelling to establish fleshy fruit traits of interest; the gene reprogramming during fruit ripening, and the ethylene dependent and independent DNA methylation changes.provides an overview on the ongoing projects and activities in the field of applied biotechnologyincludes examples of different crops and applications to be exploitedreviews  and discusses Plant Functional Genomic studies and the future developments in the fieldexplores the new technologies supporting the genetic improvement of plants

Applied Plant Genomics and Biotechnology (Woodhead Publishing Series in Biomedicine, 72)

Poltronieri, Palmiro

Hong, Yiguo

Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring.

Medical Biosensors for Point of Care (POC) Applications (Woodhead Publishing Series in Biomaterials)

Fillers and Reinforcements for Advanced Nanocomposites reviews cutting-edge, state-of-the-art research on the effective use of nanoscaled fillers and reinforcements to enhance the performance of advanced nanocomposites, both in industrial and manufacturing applications. It covers a broad range of topics such as nanocelluloses, nanotubes, nanoplatelets, and nanoparticles, as well as their extensive applications. The chapters provide detailed information on how fillers and reinforcements are used in the fabrication, synthesis and characterization of advanced nanocomposites to achieve extraordinary performance of new materials and significant enhancements in their mechanical, thermal, structural and multi-functional properties. It also highlights new technologies for the fabrication of advanced nanocomposites using innovative electrospinning techniques. Covers topics such as nanocelluloses, nanotubes, nanoplatelets, and nanoparticles, as well as their extensive applicationsDiscusses the latest research on the effective use of nanoscaled fillers and reinforcements to enhance the performance of advanced nanocompositesExplains how fillers and reinforcements are used in the fabrication, synthesis and characterization of advanced nanocomposites

Fillers and Reinforcements for Advanced Nanocomposites (Woodhead Publishing Series in Composites Science and Engineering)

Medicinal Plants: Chemistry, Biology and Omics reviews the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plant tribes and genera, and their relevance to drug efficacy. Medicinal plants provide a myriad of pharmaceutically active components, which have been commonly used in traditional Chinese medicine and worldwide for thousands of years. Increasing interest in plant-based medicinal resources has led to additional discoveries of many novel compounds, in various angiosperm and gymnosperm species, and investigations on their chemotaxonomy, molecular phylogeny and pharmacology. Chapters in this book explore the interrelationship within traditional Chinese medicinal plant groups and between Chinese species and species outside of China. Chapters also discuss the incongruence between chemotaxonomy and molecular phylogeny, concluding with chapters on systems biology and “-omics technologies (genomics, transcriptomics, proteomics, and metabolomics), and how they will play an increasingly important role in future pharmaceutical research.

Medicinal Plants: Chemistry, Biology and Omics

Gu, Xiao Jie

Hao PhD, Da-Cheng

Xiao PhD, Pei Gen

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