Duodenal Calcium Absorption & Steroid Hormones: A Transgenic Mice Study (Acta Biomedica Lovaniensia)

This is a Ph.D. dissertation. The aim of this thesis was to understand the role of 1,25(OH)2D3 and other steroid hormones in the regulation of active duodenal calcium absorption. To achieve this aim, the authors analyzed active duodenal calcium absorption at molecular and functional level. Contents include: Introduction: Calcium, The vitamin D endocrine system, Calcium (re)absorption, Active calcium absorption, vitamin D independent mechanisms; Aims and Scope of the study; Vitamin D dependent active duodenal calcium absorption; Active calcium absorption throughout the female reproductive cycle; The contribution of altered active absorption to the pathogenesis of glucocorticoid-induced bone loss; Discussion; Summary; Perspectives.