Creutzfeldt-Jakob Disease: Managing the Risk of Transmission by Blood, Plasma, and Tissues

Secondary transmissons of variant Creutzfeldt-Jakob disease (vCJD) by blood transfusion have raised serious concerns about disease transmissioon by blood components and tissue products. This multi-authored book byy international and national experts reprents a state of the art review of the basic science and pathogenesis of iatrogenically transmitted prion disease. Atimely resource, it examines the issues of blood and tissue infectivity and screening test development; a discussion of risk assessment and management completes the book. Topics of Interest: * Molecular poathology of prion diseases * Pathogenesis of peripherally trasmitted TSEs * Transmissible spongiform encephalopathies in animals and humans * Studies on peripheral blood infectivity and transmission * Development and implementation of diagnostic assays * Component processing * Plasma product manufacturing * Cell, tissue and organ transplantation * Prophylactic and therapeutic agents * Risk assessment and policy development