Eosinophilic and Autoimmune Gastrointestinal Disease: New Insights and New Entities, An Issue of Gastroenterology Clinics (Volume 37-2) (The Clinics: Internal Medicine, Volume 37-2)

Eosinophilic esophagitis (EE) is a clinicopathologic disease characterized by upper intestinal symptoms and the finding of more than 15 or 20 eosinophils in the esophageal epithelium; these findings are unresponsive to proton pump inhibitor treatment. EE is a common disease that affects both children and adults. Some of the many important topics covered include eosinophilic esophagitis in adults and children, celiac disease, autoimmune pancreatitis, autoimmune hepatitis, enteric autoantibodies and gut motility disorders, autoantibodies and inflammatory bowel disease.