Vascular Complications of Diabetes: Current Issuesin Pathogenesis and Treatment

Diabetes affects over 100 million people worldwide, and the relentless progression of diabetic vascular complications can result in disabling, multisystem morbidities. This book is aimed at healthcare professionals involved in the clinical management of these diabetic complications. Vascular Complications in Diabetes is divided into three major sections: An overview of the clinical features and evidence-based therapies for microvascular and macrovascular disease. A detailed review of diabetic retinopathy with an emphasis on diagnosis and treatment to maculopathy A description of the biochemical pathways involved in hyperglycaemia-induced structural and functional vascular abnormalities, in particular the emergence of PKC as a new therapeutic target for delaying and reversing important pathological changes in retinal, renal and endothelial tissues. Each section is fully illustrated in colour with clinical photographs and artworks as well as a Current Issues section that directs the reader to all the recent developments in this field of study.