Distance Measurements in Biological Systems by EPR

The foundation for understanding the function and dynamics of biological systems is knowledge of their structure. Many experimental methodologies are used for determination of structure, each with special utilities. The volumes in this series on Biological Magnetic Resonance emphasize the methods that involve magnetic resonance. This volume seeks to provide a critical evaluation of EPR methods for determining the distances between two unpaired electrons. The editors invited the authors to make this a very practical book, with specific numerical examples of how experimental data are worked up to produce a distance estimate, and realistic assessments of uncertainties and of the range of applicability, along with examples of the power of the technique to answer biological problems.