Molecular Basis of Inherited Disease (In Focus Series)

Progress in the molecular analysis of human genetic disease has been very rapid over the last three years since the first edition of this book was published. Most of the genes involved in the more common monogenic disorders have been identified and many of the rarer disorders have now been mapped to chromosomal regions. This thoroughly updated edition discusses these developments in detail. The techniques available for gene mapping have changed substantially thus facilitating isolation of disease genes from their chromosomal positions. Animal models are being created to allow the detailed study of disease processes. The second edition fully covers these advancements and should be a valuable reference for students, clinicians, and researchers in the biological sciences.