Over the past decades, health care delivery - once characterized by clearly defined relationships between medical professionals, regulators, and industr- has become much more complex. Traditional roles and relationships are changing and new decision-makers are entering the scene. They bring into the discussion the need for cost containment and the changing perceptions of the public with regard to the risks and benefits of health care outcomes. As benefits of medical care are increasingly questioned and as scepticism and fear of advanced technologies are demonstrated by a growing body of people, decision making must move beyond medical concerns to encompass economic, political, and sociological considera­ tions. This evolution has also affected the pharmaceutical industry. Public percep­ tion of responsibility for product safety is no longer limited to regulators and physi­ cians. Manufacturers, previously unencumbered by social policies, governmental preoccupations, or public expectations, are now held accountable for product safety. As a certain amount of risk acceptance is, however, a prerequisite for the further development of health care goods, it has to be carefully balanced against society'S demand for safety. To weigh risks against benefits, to define acceptable risk, and to exclude what no longer falls within this category remain perpetual challenges. Accordingly, health care outcomes have to be assessed not only from a clinical point of view, but also from an economic and societal perspective. The assessment of drug risks and benefits has become an important political issue world-wide.

Inventory and Supply Chain Management with Forecast Updates

Science & Math

Sethi, Suresh P.

Yan, Houmin

Zhang, Hanqin

Biological Sciences

Springer

Real problems are formulated into tractable mathematical models, which allow for an analysis of various approaches. Attention is focused on solutions. Provides a unified treatment of the models discussed , presents a critique of the existing results, and points out potential research directions.

Inventory and Supply Chain Management with Forecast Updates (International Series in Operations Research & Management Science, 81)

Business & Money

Economics

Real problems are formulated into tractable mathematical models, which allow for an analysis of various approaches. Attention is focused on solutions. Provides a unified treatment of the models discussed , presents a critique of the existing results, and points out potential research directions.

Sethi, Suresh P. P.

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