All of us have a most remarkable gene lurking in our DNA. Its job is to protect us from cancer. This gene, known simply as p53, constantly scans our cells to ensure that when they grow and divide as part of the routine maintenance of our bodies, they do so without mishap. If a cell makes a mistake in copying its DNA during the process, p53 repairs it before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control (as happens in cancer), p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or handicapped by some other fault in the system. Not surprisingly, p53 is the most studied single gene in history. p53: The Gene that Cracked the Cancer Code tells the story of the discovery of the gene and of medical science's mission to unravel its mysteries and get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, the book reveals the excitement of the hunt for new cures--the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is at the cutting edge. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

p53: The Gene that Cracked the Cancer Code

Sue Armstrong

BLOOMSBURY

From the forensic anthropologist with his own "body farm" in Tennessee to the doctor who had a heart-and-lung transplant and ended up using her own lungs for research—a jaw-dropping investigation into the world of pathology\nProfiling some of the world's most eminent and pioneering pathologists, this book—part Oliver Sacks, part crime investigation—shares many fascinating stories of mysterious illnesses and miraculous scientific breakthroughs. Topics discussed include the search for the mutations that make flu viruses deadly, doubts about the existence of "shaken baby syndrome," the quest to "build" new organs for transplantation, and what can be read in bones. It is a look into a world that is hidden, yet which everyone will encounter at some time in their lives, for pathology lies at the cornerstone of modern medicine. It is pathologists who are responsible for recognizing new diseases such as AIDS, SARS, or bird flu; for diagnosing which cancer a patient is suffering from; and for explaining the cause of death at the autopsy table. Crammed full of extraordinary characters, this book has great appeal to those interested in the extraordinary reality behind crime fiction and television dramas.

A Matter of Life and Death

Dundee University Press Ltd

The question of how and why organisms age has teased scientists for centuries. There are myriad competing theories, from the idea that ageing is a simple wear and tear process, like the rusting of a car, to the belief that ageing and death are genetically programmed and controlled. In fact, there is no clearly defined limit to life and no single, predictable program playing itself out: different things are happening within and between tissues, and each system or organ accumulates damage at its own pace, according to the kind of insults imposed on it by daily living. Sometime before 2020, the number of people over 65 worldwide will, for the first time, be greater than the number of 0-4 year olds; and by 2050 there are likely to be 2.5 times as many older people in the world as toddlers. Sue Armstrong tells the story of society's quest to understand ageing through the eyes of the scientists themselves as well as through the 'ordinary' people who exemplify the mysteries of ageing - from those who suffer from the premature ageing condition, Hutchinson-Gilford syndrome, to people still running marathons in their 80s. Borrowed Time investigates such mind-boggling experiments as transfusing young blood into old rodents and research into transplanting the first human head, among many others. It explores where science is taking us and what issues are being raised from a psychological, philosophical and ethical perspective, through interviews with, and profiles of, key scientists in the field and the people who represent interesting and important aspects of ageing.

Borrowed Time

Parenting & Relationships

Audible Studios on Brilliance Audio

We are at the early stages of understanding the disease process of cancer. It is difficult to make decisions when it comes to treating affected animals. Subjecting animals to anaesthetics and toxic drugs to achieve remission is a moral dilemma. Homeopathy is not the magic bullet for treating cancer and does not claim to be so. However, the clinical experience that Sue Armstrong has gained over thirty years of treating veterinary cancer patients that could not tolerate chemo- or radiotherapy, or whose owners could not afford to treat using these methods or refused to treat conventionally, has given her insights not only into a methodology for treating cancer cases but also into the disease process itself. In the first volume of the series, the expert vet describes the scope of homeopathy. She looks at the basics of how cancer arises, its genetic origins and the role of inflammatory processes and oxygen. Then she describes the development of homeopathic cancer treatment from Hahnemann until today, showing the successful approaches of famous homeopaths such as Kent, Grimmer, Ramakrishnan, and Burnett. Sue Armstrong describes her approach in great detail, distinguishing the various stages of cancer. In animals with a strong predisposition for cancer, a great deal can be achieved by prophylactically altering the diet and using miasmatic treatment. If the tumour is confirmed, treatment is selected according to the stage of the cancer and, for example, whether surgery is indicated. Organotropic remedies, drainage and Schuessler salts are used supportively together with the major cancer nosodes Carcinosinum and Scirrhinum. Clear instructions are also provided for treating the effects of cancer such as cachexia, disturbances in haemoptysis or vomiting. She documents her approach with impressive cases. At the end there is a concise materia medica of cancer remedies.

Cancer in Animals - What is to be cured?

See the best price to sell, buy, or rent books by Sue Armstrong. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Books by Sue Armstrong

See the best price to sell, buy, or rent books by Sue Armstrong. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

p53: The Gene that Cracked the Cancer Code

A Matter of Life and Death

Borrowed Time

Cancer in Animals - What is to be cured?