This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, Principles of Nucleic Acid Structure includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software.

Principles of Nucleic Acid Structure

Science & Math

Stephen Neidle

Biological Sciences

Academic Press

230p hardback with blue laminated boards, silver and gilt lettering, excellent fresh copy with bookplate from leading library in the field

Topics in Nucleic Acid Structure (Topics in Molecular and Structural Biology)

Chemistry

PALGRAVE~MACMILLAN

Molecular Aspects of Anticancer Drug/DNA Interactions: v. 2 (Topics in Molecular & Structural Biology)

This cutting-edge book surveys the current knowledge on the mode of action of the major classes of DNA-interactive antitumor agents, providing information that could be crucial for the discovery of new therapeutic substances. It is an important reference for molecular biologists, cancer researchers, biochemists, biophysicists, and pharmacologists.

Molecular Aspects of Anticancer Drug DNA Interactions, Vol. 2: Topics in Molecular and Structural Biology

Michael Waring

CRC-Press

Molecular Aspects of Anticancer Drug-DNA Interactions

Michael J. Waring

Bloomsbury UK

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Books by Stephen Neidle