Genes and Genomes: A Changing Perspective

The techniques which enable us to analyse and manipulate individual genes - known as Recombinant DNA Technology - have revolutionised life science during the past decade. It is with no small sense of pride that BSP announce the imminent publication of this truly historic text which combines the expertise and experience of two of the world's most eminent molecular biologists, one of whom, Professor Berg, was awarded the 1980 Nobel Prize in Chemistry for pioneering work in this area. This great work captures, for the first time, the sense of discovery, understanding and anticipation that has resulted from the fundamental recombinant DNA breakthrough. Unlike previous treatments of molecular genetics this book emphasises both depth of treatment and the experimental approach. Another innovation of the text is the explication of the subject within an historical framework that adds greatly to the logic of exposition and hence reader understanding. Beginning in Part I with a review of the status of molecular genetics in the early 1970s, the text then examines in Part II , the logic, concepts and general practices associated with gene cloning and the characterisation and manipulation of DNA. In Part III the results of the experimental paradigm are explored The changing perspective on the structure and expression of eukaryotic genes is fully brought home to the student who is then given insight into the organisation and origin of DNA sequences in eukaryotic genomes and led to an appreciation of the extent of programmed and stochastic amplifications and rearrangements that we now realise occur in what was previously considered a relatively stable genome. The unprecedented dynamism of the processes of life at the molecular level is the main theme of this monumental work.

Science & Math

Singer, Maxine

Berg, Paul.

Biological Sciences

Blackwell Science Ltd.

Dealing with Genes: The Language of Heredity

Evolution

W.H.Freeman & Company

This overview of the molecular structures and mechanisms that underlie the utilization of genetic information by complex organisms emphasizes the experimental aspects of molecular genetics. It provides a complete introduction to both principles and methods.

Business & Money

Economics

Univ Science Books

Dealing With Genes: The Language of Heredity

Those of us who read a daily newspaper or scan a weekly magazine have grown accustomed to being told that the science of genetics influences countless aspects of our existence, from human development, health, and disease to the ecological balance of our planet. We accept this, and yet most of us have only the faintest idea of what a gene really is or how it functions. This book, then, is a primer on modern genetics, and its aim is to teach any interested general reader all he or she needs to know about how genes work - and about how a detailed knowledge of their workings can be applied to some of the most pressing problems of our time. Written by two world-renowned researchers in molecular biology and illustrated with uncommon clarity and precision, Dealing with Genes will satisfy the interest of general readers, including those who have little formal background in biology. It will also serve admirably as an authoritative text for students taking nonmajors courses in biology, genetics, molecular biology, biotechnology, and related disciplines.

This collaborative work should be of interest to students and professionals in the field of biochemistry, molecular biology and genetics. The book discusses efforts to map and sequence the genomes of several species, including humans, and illustrates the depth of understanding now provided by state-of-the-art techniques in molecular biology, biochemistry and genetics. The case studies examine in detail how genes operate in complex, multicomponent and interacting systems, applying these studies to a variety of living systems including viral, cellular, and organismal models. How genotypes and thus phenotypes of individual proteins and of whole cells and organisms can be altered is also explored.

Exploring Genetic Mechanisms

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Books by Singer, Maxine