Human Experimentation: A Guided Step into the Unknown

In this accessible, philosophical guide to human experimentation, William Silverman pleads for wider use of randomized clinical trials, citing many examples that show how careful trials can overturn preconceived or ill-conceived notions of a therapy's effectiveness and lead to a clearer understanding of clinical anomalies. Because it gives careful guidance on setting up trials and avoiding conceptual pitfalls, this book will be of great interest to all epidemiologists and clinical statisticians, and to a wide variety of clinicians, pharmacologists, and nurses. Since it requires no medical or statistical knowledge, it will also appeal to ethicists, lawyers, and the general public.

Medical Books

Silverman, William A.

Research

Oxford University Press

Medicine is moving away from reliance on the proclamations of authorities to the use of numerical methods to estimate the size of effects of its interventions. But a rumbling note of uneasiness underlines present-day medical progress: the more we know, The more questions we encounter about what to do with the hard-won information. The essays in Where's the Evidence examine the dilemmas that have arisen as the result of medicine's unprecedented increase in technical powers. How do doctors draw the line between "knowing" (the acquisition of new medical information) and doing" (the application of that new knowledge)? What are the long-term consequences of responding to the demand that physicians always do everything that can be done? Is medicine's primary aim to increase the length of life? Or is it to reduce the amount of pain and suffering? And who is empowered to choose when these ends are mutually exclusive? This engaging collection of essays will be of interest to professionals interested in the evidence-based medicine debate, including epidemiologists, neonatologists, those involved in clinical trials and health policy, medical ethicists, medical students, and trainees.

Where's the Evidence?: Convtroversies in Modern Medicine (Oxford Medical Publications)

Politics & Social Sciences

Philosophy

The essays in Where's the Evidence? focus on problems ignored. This book is a unique collection of critical andw controversial essays on intractable ethical issues and evidence-based problems in modern medicine. Most, but notr therapeutic disasters. Although it is impossible to prevent all missteps in medicine, the author argues, a hedging strategy using concurrent controls when new therapies are introduced always reduces the number of patients killed or injured. It is dangerous to use treatments w+AB2idely, he warns, before they are subject to rigorous comparative trials. Additionally, the author points out, questions have emerged about how to wield medicine's new capabilities wisely. How do we draw the line,' he asks 'between "knowing" (the acquisition of new medical information) and "doing" (the application of that new knowledge). What are the long- term consequences (moral, social, economic, and biological) of responding to a demand that medicine always do everything that can be done? ' This book now issued in paperback is a collection of critical and controversial essays discussing intractable ethical issues and evidence-based problems in modern medicine. The essays together with responses were published over a ten-year period in the journal Paediatric and Perinatal Medicine. Most of the examples, but not all are taken from perinatal medicine, the field in which the author has worked for many years. The essays are thought provoking and will be of great interest to those involved in the ongoing evidence-based medicine debate. (See selected reviews)

Where's the Evidence?: Debates in Modern Medicine

"Crosscurrents" is an adventure that crosses continents and goes into the depths of the South Atlantic Ocean to accomplish the obdurate, uncompromising mission of one of history’s greatest revolutionaries.  After successfully toppling the U.S.-backed Cuban dictatorship, the legendary Che Guevara moved his armed revolution worldwide.  With only the support of his close friend Fidel Castro in Cuba and sometimes China, he quickly became a key player in the Cold War, hated and hunted by both the U.S. and Soviet Union.  A man with his own idealistic convictions about freedom, he turned his back on Soviet leaders, taunting them before the United Nations as no better than Capitalists for living in opulence while falsely preaching equality.  And people were listening.  "Crosscurrents," while a work of fiction, is solidly based on fact.  It is a story of betrayal, loyalty, greed, and the remarkable bonding between men and women of opposing convictions when confronted by a life-threatening common enemy.  It is a sometimes-brutal tale of desperate men fighting against odds in the jungles of the Congo and in Bolivia.  When the story must go aboard the world’s first deep diving submarine into the hostile depths of the South Atlantic it enters a world man has never before seen, filled with danger and the awesome reality of an unimaginable environment.  This is a novel that captures the actuality of the world after World War II when a realignment of Super Powers threatened each other with nuclear destruction.  Caught between them were millions of people whose lives were controlled by oppressive governments, countries with riches all the Super Powers plotted to seize.  Che Guevara’s cry for people to free themselves is remindful of the American Revolution when men like George Washington and signers of the Declaration of Independence might have been hung as traitors by the British had they lost.  "Crosscurrents" is a book all lovers of men willing to die for their convictions in the name of freedom should read.

Crosscurrents

Literature & Fiction

Contemporary

Dorrance Pub. Co.

"Crosscurrents" is an adventure that crosses continents and goes into the depths of the South Atlantic Ocean to accomplish the obdurate, uncompromising mission of one of history’s greatest revolutionaries. After successfully toppling the U.S.-backed Cuban dictatorship, the legendary Che Guevara moved his armed revolution worldwide. With only the support of his close friend Fidel Castro in Cuba and sometimes China, he quickly became a key player in the Cold War, hated and hunted by both the U.S. and Soviet Union. A man with his own idealistic convictions about freedom, he turned his back on Soviet leaders, taunting them before the United Nations as no better than Capitalists for living in opulence while falsely preaching equality. And people were listening. "Crosscurrents," while a work of fiction, is solidly based on fact. It is a story of betrayal, loyalty, greed, and the remarkable bonding between men and women of opposing convictions when confronted by a life-threatening common enemy. It is a sometimes-brutal tale of desperate men fighting against odds in the jungles of the Congo and in Bolivia. When the story must go aboard the world’s first deep diving submarine into the hostile depths of the South Atlantic it enters a world man has never before seen, filled with danger and the awesome reality of an unimaginable environment. This is a novel that captures the actuality of the world after World War II when a realignment of Super Powers threatened each other with nuclear destruction. Caught between them were millions of people whose lives were controlled by oppressive governments, countries with riches all the Super Powers plotted to seize. Che Guevara’s cry for people to free themselves is remindful of the American Revolution when men like George Washington and signers of the Declaration of Independence might have been hung as traitors by the British had they lost. "Crosscurrents" is a book all lovers of men willing to die for their convictions in the name of freedom should read.

Dorrance Publishing

Retrolental Fibroplasia: A Modern Parable

Medicine

Grune Stratton

See the best price to sell, buy, or rent books by Silverman, William A.. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Books by Silverman, William A.

See the best price to sell, buy, or rent books by Silverman, William A.. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Human Experimentation: A Guided Step into the Unknown

Where's the Evidence?: Convtroversies in Modern Medicine (Oxford Medical Publications)

Where's the Evidence?: Debates in Modern Medicine

Crosscurrents

Crosscurrents

Retrolental Fibroplasia: A Modern Parable