Applied Surrogate Endpoint Evaluation Methods with SAS and R (Chapman & Hall/CRC Biostatistics Series)

An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment’s efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.

Science & Math

Burzykowski, Tomasz

Shkedy, Ziv

Molenberghs, Geert

Alonso, Ariel

Bigirumurame, Theophile

Buyse, Marc

Muchene, Leacky

Perualila, Nolen Joy

Van der Elst, Wim

Biological Sciences

Chapman and Hall/CRC

Praise for the First Edition “…extremely well written…a comprehensive and up-to-date overview of this important field.” – Journal of Environmental Quality Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition provides comprehensive coverage of recent advancements in microarray data analysis. A cutting-edge guide, the Second Edition demonstrates various methodologies for analyzing data in biomedical research and offers an overview of the modern techniques used in microarray technology to study patterns of gene activity. The new edition answers the need for an efficient outline of all phases of this revolutionary analytical technique, from preprocessing to the analysis stage. Utilizing research and experience from highly-qualified authors in fields of data analysis, Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition features: <ul>
<li>A new chapter on the interpretation of findings that includes a discussion of signatures and material on gene set analysis, including network analysis</li> <li>New topics of coverage including ABC clustering, biclustering, partial least squares, penalized methods, ensemble methods, and enriched ensemble methods</li> <li>Updated exercises to deepen knowledge of the presented material and provide readers with resources for further study</li> </ul> The book is an ideal reference for scientists in biomedical and genomics research fields who analyze DNA microarrays and protein array data, as well as statisticians and bioinformatics practitioners. Exploration and Analysis of DNA Microarray and Other High-Dimensional Data, Second Edition is also a useful text for graduate-level courses on statistics, computational biology, and bioinformatics.

Exploration and Analysis of DNA Microarray and Other High-Dimensional Data (Wiley Series in Probability and Statistics)

Cabrera, Javier

Amaratunga, Dhammika

wiley

This guide to the latest statistical techniques for estimating the parameters of infectious diseases arises from a groundbreaking collaboration between Hasselt and Antwerp universities in Belgium, and features valuable case studies and software advice.

Modeling Infectious Disease Parameters Based on Serological and Social Contact Data: A Modern Statistical Perspective (Statistics for Biology and Health, 63)

Hens, Niel

Aerts, Marc

Faes, Christel

Van Damme, Pierre

Beutels, Philippe

Springer

See the best price to sell, buy, or rent books by Shkedy, Ziv. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Books by Shkedy, Ziv