A complete account of the theory of the diffraction of X-rays by crystals, with particular reference to the processes of determining the structures of protein molecules. This book is aimed primarily at structural biologists and biochemists but will also be valuable to those entering the field with a background in physical sciences or chemistry. It may be used at any post-school level, and develops from first principles all relevant mathematics, diffraction and wave theory, assuming no mathematical knowledge beyond integral calculus. The book covers a host of important topics in the area, including: - The practical aspects of sample preparation and X-ray data collection, using both laboratory and synchrotron sources - Data analysis at both theoretical and practical levels - The important role played by the Patterson function in structure analysis, by both molecular replacement and experimental phasing approaches - Methods for improving the resulting electron density map - The theoretical basis of methods used in refinement of protein crystal structures - In-depth explanation of the crucial task of defining the binding sites of ligands and drug molecules - The complementary roles of other diffraction methods: these reveal further detail of great functional importance in a crystal structure.

Crystals, X-rays and Proteins: Comprehensive Protein Crystallography

Reference

Sherwood, Dennis

Words, Language & Grammar

Oxford University Press

Modern Thermodynamics for Chemists and Biochemists

Thermodynamics is fundamental to university and college curricula in chemistry, physics, engineering and many life sciences around the world. It is also notoriously difficult for students to understand, learn and apply. What makes this book different, and special, is the clarity of the text. The writing style is fluid, natural and lucid, and everything is explained in a logical and transparent manner. Thermodynamics is a deep, and important, branch of science, and this book does not make it "easy". But it does make it intelligible. This book introduces a new, 'Fourth Law' of Thermodynamics' based on the notion of Gibbs free energy, which underpins almost every application of thermodynamics and which the authors claim is worthy of recognition as a 'law'. The last four chapters bring thermodynamics into the twenty-first century, dealing with bioenergetics (how living systems capture and use free energy), macromolecule assembly (how proteins fold), and macromolecular aggregation (how, for example, virus capsids assemble). This is of great current relevance to students of biochemistry, biochemical engineering and pharmacy, and is covered in very few other texts on thermodynamics. The book also contains many novel and effective examples, such as the explanation of why friction is irreversible, the proof of the depression of the freezing point, and the explanation of the biochemical standard state.

Science & Math

Dalby, Paul

Biological Sciences

A complete account of the theory of the diffraction of x-rays by crystals with particular reference to the processes of determining the structures of protein molecules, this book is aimed primarily at structural biologists and biochemists but will also be valuable to those entering the field with a background in physical sciences or chemistry. It may be used at any post-school level, and develops from first principles all relevant mathematics, diffraction and wave theory, assuming no mathematical knowledge beyond integral calculus. The book covers a host of important topics in the area, including: - The practical aspects of sample preparation and x-ray data collection, using both laboratory and synchrotron sources - Data analysis at both theoretical and practical levels - The important role played by the Patterson function in structure analysis by both molecular replacement and experimental phasing approaches - Methods for improving the resulting electron density map - The theoretical basis of methods used in refinement of protein crystal structures - In-depth explanation of the crucial task of defining the binding sites of ligands and drug molecules - The complementary roles of other diffraction methods which reveal further detail of great functional importance in a crystal structure.

Cooper, Jon

A complete account of the theory of the diffraction of X-rays by crystals, with particular reference to the processes of determining the structures of protein molecules. This book is aimed primarily at structural biologists and biochemists but will also be valuable to those entering the field with a background in physical sciences or chemistry. It may be used at any post-school level, and develops from first principles all relevant mathematics, diffraction and wave theory, assuming no mathematical knowledge beyond integral calculus. The book covers a host of important topics in the area, including:- The practical aspects of sample preparation and X-ray data collection, using both laboratory and synchrotron sources - Data analysis at both theoretical and practical levels- The important role played by the Patterson function in structure analysis, by both molecular replacement and experimental phasing approaches - Methods for improving the resulting electron density map - The theoretical basis of methods used in refinement of protein crystal structures - In-depth explanation of the crucial task of defining the binding sites of ligands and drug molecules - The complementary roles of other diffraction methods: these reveal further detail of great functional importance in a crystal structure.

Crystals, X-Rays, and Proteins

Chemistry

John Wiley&Sons

Crystals, X-rays, and proteins

Longman

All scientists and engineers are creative - you wouldn't be a scientist or engineer if you weren't. But can you be even more creative? Do you know how to develop creativity in those who are less confident? And how to build a team culture in which creativity flourishes? If those questions spark interest, then this book is for you. Presenting pragmatic and powerful processes for generating ideas, and for distinguishing good ideas from weak ones, the book explores the fundamental first principles on which creativity is based, as well as the organisational factors that need to be addressed for creativity to happen. Filled with examples of creativity in science and engineering, and including a contributed chapter in which 13 contemporary scientists and engineers tell their own stories, this book is a practical 'how to' guide on how to have good ideas on demand, how to judge between good ideas and bad ones, and how to build a sustainable innovation culture. From gravitational waves to outreach, from safety on trains to how some cows in Kansas triggered an idea for noise reduction, the examples in this book are sure to stimulate individual and organisational creativity. Key Features: <ul><li>Provides a practical 'how to' guide on how to have good ideas 'on demand'</li><li>Shows how to identify, wisely, the best ideas</li><li>Presents down-to-earth strategies to increase scientific creativity</li><li>Includes stimulating case studies contributed by 16 leading scientists and engineers</li><li>Describes how to build a sustainable organisational culture in which creativity can flourish</li><li>Written by a world leader in creative consultancy</li></ul>

Creativity for Scientists and Engineers

Behavioral Sciences

IOP Publishing Ltd.

Strategic Thinking Illustrated: Strategy Made Visual Using Systems Thinking

This book is about the behaviour of systems. Systems are important, for we interact with them all the time, and many of the actions we take are influenced by a system – for example, the system of performance measures in an organisation influences, often very strongly, how individuals within that organisation behave. Furthermore, sometimes we are involved in the design of systems, as is any manager contributing to the definition of what those performance measures might be. That manager will want to ensure that all the proposed performance measures will drive the ‘right’ behaviours rather than (inadvertently) encouraging dysfunctional ‘game playing’, and so anticipating how the performance measurement system will work in practice is a vital part of a wise design process. 
Some of the systems with which we interact are local, such as your organisation’s performance measurement system. Some systems, however, are distant, but nonetheless very real, such as the healthcare system, the education system, the legal system and the climate system. Systems, therefore, exist on all scales, from the local to the global. And all systems are complex, some hugely so. That’s why understanding how systems behave can be very helpful. 
Systems are complex for two main reasons. First, the manner in which they behave over time can be very hard to anticipate – and anticipating the future sensibly is of course a key objective of management. Second, the ‘entities’ within a system can be connected together in very complex ways, so that an intervention ‘here’ can result in an effect ‘there’, perhaps a long time afterward. Sometimes this can be surprising, and so we talk of ‘unintended consequences’ – but this is of course a euphemism for ‘because I didn’t understand how this system behaves, I had not anticipated that’. 
Systems thinking, the subject matter of this book, is the disciplined study of systems, and causal loop diagrams – the ‘pictures’ of this ‘picture book’ – are a very insightful way to represent the connectedness of the entities from which any system is composed, so taming that system’s complexity.

Business & Money

Business Culture

Productivity Press

Smart people recognise that innovation and creativity aren't the same thing. Leading out-of-the-box guru shows you how to fill your life and organisation with both.

Smart Things to Know About, Smart Things to Know About Innovation & Creativity

Capstone

See the best price to sell, buy, or rent books by Sherwood, Dennis. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Books by Sherwood, Dennis

See the best price to sell, buy, or rent books by Sherwood, Dennis. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Crystals, X-rays and Proteins: Comprehensive Protein Crystallography

Modern Thermodynamics for Chemists and Biochemists

Modern Thermodynamics for Chemists and Biochemists

Crystals, X-rays and Proteins: Comprehensive Protein Crystallography

Crystals, X-Rays, and Proteins

Crystals, X-rays, and proteins

Creativity for Scientists and Engineers

Strategic Thinking Illustrated: Strategy Made Visual Using Systems Thinking

Strategic Thinking Illustrated: Strategy Made Visual Using Systems Thinking

Smart Things to Know About, Smart Things to Know About Innovation & Creativity