Book by Roth, Jack A., Ruckdeschel, John C., Weisenburger, Thomas H.

Thoracic Oncology

Roth, Jack A.

Ruckdeschel, John C.

Weisenburger, Thomas H.

Medical Books

W.B.Saunders Co.

Lung cancer is a leading cause of death in men and women, but until recently there has been little new to say in terms of diagnosis and treatment. This situation has changed with the arrival of - for instance - magnetic resonance imaging for more efficient diagnosis, and new treatment in the form of new surgical approaches, the use of lasers and adjuvant treatment (the boosting of the immune system). This volume concentrates on, and puts into perspective, the most recent and exciting advances, assuming basic knowledge of oncology and pulmonary and thoracic surgery.

Lung Cancer

Health, Fitness & Dieting

Cox, James D.

Diseases & Physical Ailments

Blackwell Science Inc.

An overview of the p53 gene covering the role of p53 in cancer; gene structure; wild-type versus mutant p53 ; biophysical and biochemical properties of the p53 protein; regulation and modulation of the function of p53 ; and the potential clinical significance of the p53 tumor suppressor gene in cancer patients. Annotation copyright Book News, Inc. Portland, Or.

P53 Suppressor Gene (Molecular Biology Intelligence Unit)

Mukhopadhyay, Tapas

Maxwell, Steven A.

Science & Math

R G Landes Co

This book is about the p53 gene, one of the most frequently mutated or deleted genes in human cancers. The frequent occurrence of inactivated p53 implicates this gene product in the genesis of many human cancers. The p53 gene can suppress the growth of cancer cells and the transformation process by oncogenes. The p53 protein is a transcription factor that can repress or activate promoters containing one of three p53 DNA-binding motifs. The activity of p53 is regulated by phosphorylation and other transcription factors. Replacement of the p53 function or restoration of the p53 biochemical pathway is a focus of gene therapy.

p53 Suppressor Gene (Molecular Biology Intelligence Unit)

Biological Sciences

Springer

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Books by Roth, Jack A.