Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomena in different ways, the Sante Fe Institute and the Theoretical Division of Los Alamos National Laboratory cosponsored a workshop entitled "Theoretical Immunology". The workshop focused on themes spanning the field of immunology, with emphasis on areas where the theorists have made the most progress. This book covers the discussions a that workshop on the topics of immune surveillance, mathematical models of HIV infection, complexities of antigen-antibody systems, immune suppression and tolerance, and idiotypie networks. In each of these areas there is reason to believe that advances can be made either through interactions among experimentalists and theorists or through the critical look experimentalists and theorists will bring to bear upon one another's work.

Theoretical Immunology, Part One: The Proceedings of the Theoretical Immunology Workshop, Held June, 1987 in Santa FE, New Mexico (Santa Fe Institute Series)

Science & Math

Perelson, Alan S.

Biological Sciences

Westview Press

Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomena in different ways, the Sante Fe Institute and the Theoretical Division of Los Alamos National Laboratory cosponsored a workshop entitled "Theoretical Immunology." The workshop focused on themes spanning the field of immunology, with emphasis on areas where the theorists have made the most progress. This book covers the discussions a that workshop on the topics of immune surveillance, mathematical models of HIV infection, complexities of antigen-antibody systems, immune suppression and tolerance, and idiotypie networks. In each of these areas there is reason to believe that advances can be made either through interactions among experimentalists and theorists or through the critical look experimentalists and theorists will bring to bear upon one another's work.

Theoretical Immunology, Part Two: The Proceedings of the Theoretical Immunology Workshop, Held June, 1987 in Santa FE, New Mexico (Santa Fe Institute Series)

Brand new(never opened)!!/No dust jacket as issued -ships immediately

Molecular Evolution On Rugged Landscapes: Proteins, Rna, And The Immune System (volume Ix) (Proceedings Volume in the Santa Fe Institute Studies in the Sciences of Complexity, V. 9.)

Health, Fitness & Dieting

Diseases & Physical Ailments

Addison-Wesley

This book lays out a number of the general issues concerning the structure of rugged fitness landscapes and examines both the history and the current status of experimental work on somatic mutation and the maturation of the immune response.

Molecular Evolution on Rugged Landscapes: Protein, RNA, and the Immune System (Volume IX) (Santa Fe Institute Series)

Kauffman, Stuart A.

CRC-Press

Theoretical Immunology, Part One: The Proceedings of the Theoretical Immunology Workshop, Held June, 1987 in Santa FE, New Mexico (Theoretical Immunology, 1)

Assuming that the complex phenomena underlying the operation of the immune system may be better understood through the collaborative efforts of theorists and experimentalists viewing the same phenomena in different ways, the Sante Fe Institute and the Theoretical Division of Los Alamos National Laboratory cosponsored a workshop entitled "Theoretical Immunology." The workshop focused on themes spanning the field of immunology, with emphasis on areas where the theorists have made the most progress. This book covers the discussions a that workshop on the topics of immune surveillance, mathematical models of HIV infection, complexities of antigen-antibody systems, immune suppression and tolerance, and idiotypie networks. In each of these areas there is reason to believe that advances can be made either through interactions among experimentalists and theorists or through the critical look experimentalists and theorists will bring to bear upon one another's work.

Theoretical Immunology, Part Two: The Proceedings of the Theoretical Immunology Workshop, Held June, 1987 in Santa FE, New Mexico (Theoretical Immunology, 2)

The body contains many cellular systems that require the continuous production of new, fully functional, differentiated cells to replace cells lacking or having limited self-renewal capabilities that die or are damaged during the lifetime of an individual. Such systems include the epidermis, the epithelial lining of the gut, and the blood. For example, erythrocytes (red blood cells) lack nuclei and thus are incapable of self-replication. They have a life span in the circulation of about 120 days. Mature granulocytes, which also lack proliferative capacity, have a much shorter life span - typically 12 hours, though this may be reduced to only two or three hours in times of serious tissue infection. Perhaps a more familiar example is the outermost layer of the skin. This layer is composed of fully mature, dead epidermal cells that must be replaced by the descendants of stem cells lodged in lower layers of the epidermis (cf. Alberts et al. , 1983). In total, to supply the normal steady-state demands of cells, an average human must produce approximately 3. 7 x 1011 cells a day throughout life (Dexter and Spooncer, 1987). Common to each of these cellular systems is a primitive (undifferentiated) stem cell which replenishes cells through the production of offspring, some of which proliferate and gradually differentiate until mature, fully functional cells are produced.

Stem Cell Proliferation and Differentiation: A Multitype Branching Process Model (Lecture Notes in Biomathematics, 76)

Macken, Catherine A.

Springer

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