Occupational epidemiology has emerged as a distinct subdiscipline of epidemiology and occupational medicine, addressing fundamental public health and scientific questions relating to the specification of exposure-response relationships, assessment of the adequacy of occupational exposure guidelines, and extrapolation of hazardous effects to other settings. This book reviews the wide range of principles and methods used in epidemiologic studies of working populations. It describes the historical development of occupational epidemiology, the approaches to characterizing workplace exposures, and the methods for designing and implementing epidemiologic studies. The relative strengths and limitations of different study designs are emphasized. Also included are more advanced discussions of statistical analysis, the estimation of doses to biological targets, and applications of the data derived from occupational epidemiology studies to disease modeling and risk assessment. The volume will serve both as a textbook in epidemiology and occupational medicine courses and as a practical handbook for the design, implementation, and interpretation of research in this field.

Research Methods in Occupational Epidemiology (Monographs in Epidemiology and Biostatistics, 13)

Science & Math

Checkoway, Harvey

Pearce, Neil

Crawford-Brown, Douglas J.

Biological Sciences

Oxford University Press, USA

Asthma prevalence is increasing worldwide, and there is growing concern about the burden of asthma both for patients and for the health sevices. There have also been major changes in the way in which the management of asthma death in some western countries in the 1960's and again in the 1970's. Asthma epidemiology has a major role to play in investigating the causes of these global changes, and in developing preventive interventions. This is the first text on the principles and methods of asthma epidemiology. It describes the types of asthma epidemiology studies, and discusses the strengths and limitations of the various methods of measuring asthma prevalence and asthma morbidity and the major risk factors for asthma, methods of studying the causes of asthma deaths. The book will therefore be of interest not only to epidemiologists, but also to the very large number of respiratory physicians, allergist, and pediatricians who are becoming involved in asthma epidemiology.

Asthma Epidemiology: Principles and Methods

Health, Fitness & Dieting

Beasley, Richard

Burgess, Carl

Crane, Julian

Diseases & Physical Ailments

Oxford University Press

This widely used text provides a clear and critical summary of research approaches to the epidemiological study of workplace hazards. It describes the historical development of occupational epidemiology, methods for characterizing occupational exposures, and techniques for designing and implementing epidemiologic studies in this area. The relative strengths and limitations of various study designs for investigating specific health outcomes are emphasized. Also included are more advanced discussions of statistical analysis, exposure and dose modeling, and subsequent applications of data derived from epidemiologic research, as in meta-analysis, pooled analysis, and statistical analysis, exposure and dose modeling, and risk assessment. Since the first edition was published 15 years ago, there have been numerous advances in epidemiologic methods to accommodate a broadened scope of investigations of occupational exposures and associated adverse health outcomes. Thus, in this Second Edition the authors have updated their discussions of methodology to include such topics as case-cohort and case-crossover designs and statistical analysis of repeated measures data, and have expanded the examples they use throughout the book to demonstrate the applications of these methods to a wide range of acute and chronic health outcomes. They have also added a new chapter on occupational health sureillance. Their text is unique for its strong emphasis on the definition and assessment of exposures, the application of quantitative exposure data to epidemiologic models, and the recognition that improvements in workplace risk identification and quantification will come from careful integration of these approaches. This fine volume will serve both as a textbook for courses on occupational epidemiology and as a practical handbook of the design, implementation, and evaluation of research in this field.

Research Methods in Occupational Epidemiology (Monographs in Epidemiology and Biostatistics)

Kriebel, David

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Books by Pearce, Neil