Risk Assessment for Human Metal Exposures: Mode of Action and Kinetic Approaches examines the current principles of risk assessment in human metal exposures, with a focus on Mode of Action(MOA), Toxicokinetic and Toxicodynamic (TKTD) considerations, and computer models. Derived from the highly respected Handbook on the Toxicology of Metals, Fourth Edition (2014), the book summarizes principles and methods and provides examples of how MOA –TKTD can be used. In addition, it presents tactics on how information generated by such methods can be confirmed by epidemiological data. Furthermore, it demonstrates how epidemiological data can be confirmed and evaluated by the examined models and considerations. This resource uniquely integrates several important topics, such as risk assessment, characterization, management and communication―the classic risk assessment paradigm―with mode of action, TKTD, and epidemiology, all topics related to human exposure. Written by pioneers in the field, this book is an essential reference for researchers, students and technicians in toxicology and risk assessment.

Risk Assessment for Human Metal Exposures: Mode of Action and Kinetic Approaches

Medical Books

Nordberg, Gunnar F.

Fowler, Bruce A.

Pharmacology

Academic Press

This handbook aims to provide a comprehensive review of the biological effects of metals that are relevant for an understanding and evaluationof their toxicity. It is divided into 2 parts, the first of which deals with general aspects of metal toxicity; the second part comprises 28 chapters each dealing with a specific metal. The handbook provides easy assess to basic toxicological data as well as in-depth treatment of this information. A large number of references are included for those in search of more detailed information.

Handbook on the Toxicology of Metals: General Aspects

Science & Math

Friberg, Lars

Biological Sciences

Elsevier Science Ltd.

Handbook on the Toxicology of Metals: Specific Metals

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Books by Nordberg, Gunnar F.