Filled with industrial examples emphasizing the practical applications of crystallization methodologies 
Based on the authors' hands-on experiences as process engineers at Merck, Crystallization of Organic Compounds guides readers through the practical aspects of crystallization. It uses plenty of case studies and examples of crystallization processes, ranging from development through manufacturing scale-up. The book not only emphasizes strategies that have been proven successful, it also helps readers avoid common pitfalls that can render standard procedures unsuccessful. The goal of this text is twofold: <ul>
<li>Build a deeper understanding of the fundamental properties of crystallization as well as the impact of these properties on crystallization process development.</li> <li>Improve readers' problem-solving abilities by using actual industrial examples with real process constraints.</li> </ul>
Crystallization of Organic Compounds begins with detailed discussions of fundamental thermodynamic properties, nucleation and crystal growth kinetics, process dynamics, and scale-up considerations. Next, it investigates modes of operation, including cooling, evaporation, anti-solvent, and reactive crystallization. The authors conclude with special applications such as ultrasound in crystallization and computational fluid dynamics in crystallization. Most chapters feature multiple examples that guide readers step by step through the crystallization of active pharmaceutical ingredients (APIs). With its focus on industrial applications, this book is recommended for chemical engineers and chemists who are involved with the development, scale-up, or operation of crystallization processes in the pharmaceutical and fine chemical industries.

Crystallization of Organic Compounds: An Industrial Perspective

Science & Math

McCauley, James A.

Tung, Hsien-Hsin

Paul, Edward L.

Midler, Michael

Chemistry

Wiley-AIChE

Crystallization of Organic Compounds 
Practical resource covering applications of crystallization principles with methodologies, case studies, and numerous industrial examples for emphasis 
Based on the authors’ hands-on experiences as process engineers, through the use of case studies and examples of crystallization processes, ranging from laboratory development through manufacturing scale-up, Crystallization of Organic Compounds guides readers through the practical applications of crystallization and emphasizes strategies that have proven to be successful, enabling readers to avoid common pitfalls that can render standard procedures unsuccessful. 
Most chapters feature multiple examples that guide readers, step by step, through the crystallization of active pharmaceutical ingredients (APIs), including an analysis of the major methods of carrying out crystallization operations, their strengths and potential issues, as well as numerous examples of crystallization processes from development through manufacturing scale. 
Advancements in the field of crystallization have been integrated throughout the book in the newly revised Second Edition to ensure the content adequately reflects current state-of-the-art industrial know-hows and practice. The new edition also adds chapters addressing downstream operations after the crystallization, including filtration/washing and drying, together with industrial use cases. 
Crystallization of Organic Compounds includes detailed information on: Solubility and solid behavior, covering phase rule, polymorph, salt/co-crystal, chiral resolution and in-silico solubility prediction; and kinetics, covering seed, supersaturation, nucleation, crystal growth and model-based experimental design Critical issues in the crystallization practice, covering oiling out, seeding/wet-milling, agglomeration/aggregation, mixing scale-up and quality-by-design principles Cooling, anti-solvent, evaporation and reactive crystallization process design, covering batch and continuous operations with industrial examples Special applications, covering crystallization with ultrasound, reaction selectivity enhancement, and computation fluid dynamics, and solid dispersion 
With highly practical coverage of the subject, Crystallization of Organic Compounds is an essential resource for engineers and chemists involved with the development, scaling, or operation of crystallization process in the pharmaceutical and fine chemical industries, particularly those with degrees in chemical engineering and chemistry.

Crystallization Of Organic Compounds

[Hoboken, New Jersey] : Wiley

Bible Journal: Note Taking, One Line A Day, Every Chapter Listed with Space for Notes, (5"x8"), 318 pages

Religion & Spirituality

Christian Books & Bibles

Independently published

Bible Journal: Note Taking with Blank Pages, Every Bible Chapter Listed with Space for Notes for One Line A Day, Favorite and Key Verses, Questions, ... Inspirational Writer, NEW (5"x8"), 318 pages

Education & Teaching

Studying & Workbooks

Bible Journal: Note Taking, One Line A Day, Easter, Every Chapter Listed with Space for Notes, (5"x8"), 318 pages

NOTES FOR ALL BIBLE CHAPTERS Enjoy your Bible Journal. When you open your Bible Journal you will find every Bible chapters in order by book with space for journaling. Note-Taking for every chapter to The Book of Genesis to Revelation. All in One. Bible Journal for Teaching, Church, and Personal Study. &nbsp; &nbsp; CARRY AROUND LESS Space to take notes for all the chapters of the Bible in order from Genesis to Revelation. All of your notes in one journal for all the chapters in the entire Bible. Fewer tablets or journals you have to carry around. Now you will have 300 plus pages to fill with your content. Create a great organized resource. See your growth over the years. &nbsp; &nbsp; SERIOUS STUDYING Great for biblical character and topical studying. If you are a seminary student or take bible classes, you will definitely find this handy. Going from class to class placing all of your notes into one journal that is ready to fill in with your insight. &nbsp; &nbsp; STRESS-FREE NOTE-TAKING If you want to remember what you've learned within a certain chapter you can leave a note on what you learned after reading. What is the main idea you learned from reading a chapter of the Bible can now be recorded in your journal? &nbsp; &nbsp; PERSONAL BIBLE STUDY Give yourself a few things to seek when reading your Bible. How does the passage relate to your life? What is God saying to you through the reading of the bible? What is your favorite verse of a chapter? What is something you want to explore later from a chapter? What is something you never want to forget about from a chapter of the bible? Write reminders on what you want in your journal. &nbsp; &nbsp; SHARING VERSES WITH OTHERS Want to place names in the journal to share key details on a passage for a family member, friend, or colleague to review when you see them? Place their name in the blank journaling space as a reminder to share it with them. Do you have a particular group, maybe a bible group you want to share something with? Church group, Sunday school? Jot a note for them in your journal. &nbsp; &nbsp; USED BY ALL AGES Doesn't matter if you a serious Bible reader or a casual reader your Bible Journal will still benefit you in many ways. &nbsp; &nbsp; MAIN RESOURCE If you have other Biblical resources such as commentary, topical Bibles, and other books you are reading that complement the Bible, what better way than to put your notes and reference points in your Bible Journal? You will be pleased with this Bible Journal. &nbsp; &nbsp; EDUCATORS For teachers and professors of the Bible, this is great for your students. Serves as a potential workbook for test preparation and other academic purposes. &nbsp; BIBLE COMPANION This is not a bible. This is an awesome Bible Companion to have with any version of the Bible you prefer. &nbsp; &nbsp; DIFFERENT COLOR OPTIONS A variety of different colorways submitted for your color preference.&nbsp;We plan to make different styles, colors, patterns available on Amazon. In the search field, you can search for "bible journal james a. mccauley" to see different options. You can click the blue hyperlink "James A. McCauley" under the book title to view all the books I've published on Amazon. Great for gifting to others as well. Neutral, school, team, and church colors are where we get the color scheme from. Purchase the Bible Journal that fits your preference. Thank you in advance. GOD BLESS. - JMc

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