Fundamentals of Analytical Toxicology is an integrated introduction to the analysis of drugs, poisons, and other foreign compounds in biological and related specimens. Assuming only basic knowledge of analytical chemistry, this invaluable guide helps trainee analytical toxicologists understand the principles and practical skills involved in detecting, identifying, and measuring a broad range of compounds in various biological samples. Clear, easy-to-read chapters provide detailed information on topics including sample collection and preparation, spectrophotometric and luminescence techniques, liquid and gas-liquid chromatography, and mass spectrometry including hyphenated techniques. This new edition contains thoroughly revised content that reflects contemporary practices and advances in analytical methods. Expanding the scope of the 1995 World Health Organization (WHO) basic analytical toxicology manual, the text includes coverage of separation science, essential pharmacokinetics, xenobiotic absorption, distribution and metabolism, clinical toxicological and substance misuse testing, therapeutic drug monitoring, trace elements and toxic metals analysis, and importantly the clinical interpretation of analytical results. Written by a prominent team of experienced practitioners, this volume: <ul>
<li>Focuses on analytical, statistical, and pharmacokinetic principles</li> <li>Describes basic methodology, including colour tests and immunoassay and enzyme-based assays</li> <li>Outlines laboratory operations, such as method validation, quality assessment, staff training, and laboratory accreditation</li> <li>Follows IUPAC nomenclature for chemical names and recommended International Non-proprietary Name (rINN) for drugs and pesticides</li> <li>Includes discussion of 'designer drugs' (novel pharmaceutical substances NPS)</li> </ul>
Fundamentals of Analytical Toxicology: Clinical and Forensic, 2nd Edition is an indispensable resource for advanced students and trainee analytical toxicologists across disciplines, such as clinical science, analytical chemistry, forensic science, pathology, applied biology, food safety, and pharmaceutical and pesticide development.

Fundamentals of Analytical Toxicology: Clinical and Forensic

Science & Math

Whelpton, Robin

Flanagan, Robert J.

Maurer, Hans H.

Cuypers, Eva

Chemistry

wiley

The new edition of this famous collection:* triples the number of spectra* now includes pesticides and pollutants* also allows identification of doping agents* offers nearly complete coverage of centrally active drugs, designer drugs, registered pesticides, pollutants, organic solvents All the spectra were obtained in the authors' laboratory using GC-MS coupling techniques.As the subtitle (in its new wording) suggests, the collection now reaches far beyond the needs of clinical toxicologists and pharmacologists. Above all, the inclusion of pesticides and pollutants makes this data collection invaluable for environmental chemists, occupational toxicologists and food analysts as well. Unmatched in scope, quality and reliability, this collection is the result of a unique effort. It is indispensable for laboratories in this field all over the world.

Parts 1, 2, 3, Mass Spectral and GC Data, 2nd Edition

Pfleger, Karl

Weber, Armin A.

Weber, A.

Maurer, H. H.

Pfleger, K.

Wiley-VCH

Announcing a new volume of Pfleger/Maurer/Weber: Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites. Unmatched in scope, quality and reliability, this collection is the result of a unique effort.Part 4 of this famous reference work contains- 2000 new mass spectra (more than 6300 in Part 1-4)- data of nearly all the new drugs relevant to clinical and forensic toxicology, doping control, food chemistry, etc.- nearly complete coverage of trimethylsilylated, perfluoroacylated, perfluoroalkylated and methylated compounds- data revision of already published volumes in this second edition- updated sections on sample preparation and GC-MS methods- tables covering all the data of Parts 1-4 with directions as to page and volume on/in which the data can be found as well as the appropriate entry numbers of the electronic versions (tables listed by names and categories). The complete set of Part 1-4 now comprises more than 6300 mass spectra and reaches far beyond the needs of clinical and forensic toxicologists. The inclusion of pesticides and pollutants makes this data collection invaluable for environmental chemists, occupational toxicologists and food analysts, too.The data of the supplement volume will also be provided as an up-grade of the computer libraries (PMW_TOX3) by producers of mass spectrometers, e.g., Hewlett Packard, Finnigan (MAT, CE, Automass), Shimadzu and Varian.

Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites (Part IV)

Announcing a new volume of Pfleger/Maurer/Weber: Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites. Unmatched in scope, quality and reliability, this collection is the result of a unique effort.  The new Part 4 of this famous reference work contains  - 2000 new mass spectra (more than 6300 in Part 1-4) - data of nearly all the new drugs relevant to clinical and forensic toxicology, doping control, food chemistry, etc. - nearly complete coverage of trimethylsilylated, perfluoroacylated, perfluoroalkylated and methylated compounds - data revision of already published volumes in this second edition - updated sections on sample preparation and GC-MS methods - tables covering all the data of Parts 1-4 with directions as to page and volume on/in which the data can be found as well as the appropriate entry numbers of the electronic versions (tables listed by names and categories).   The complete set of Part 1-4 now comprises more than 6300 mass spectra and reaches far beyond the needs of clinical and forensic toxicologists. The inclusion of pesticides and pollutants makes this data collection invaluable for environmental chemists, occupational toxicologists and food analysts, too.  The data of the supplement volume will also be provided as an up-grade of the computer libraries (PMW_TOX3) by producers of mass spectrometers, e.g., Agilent Technologies, Thermo Finnigan, Perkin-Elmer, Shimadzu and Varian.

Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites, Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites: Parts I-IV

This unique collection contains data obtained from clinical samples over the course of more than 20 years. It encompasses 7500 potentially harmful substances, from simple analgesics to designer drugs, and from pesticides to chemical warfare agents. Since these substances are often broken down in the human body, metabolites are also included, so as to allow quick and unambiguous identification of the mother substance. The 3rd edition gives all spectra in order of their molecular mass, since this has become the prime benchmark criterion for the identification of unknown substances.

Mass Spectral And GC Data of Drugs, Poisons, Pesticides, Pollutants And Their Metabolites

Vch Verlagsgesellschaft Mbh

The world's most comprehensive reference for forensic toxicologists is keeping pace with recent developments in clinical toxicology in its new release: Another 800 new spectra have been added to this gold standard, including novel designer drugs and a broad range of AIDS therapeutics, for a total of 8,650 clinically relevant substances, including 5,200 metabolites. The print edition contains a comprehensive listing of all compounds in order of molecular mass, showing a reference mass spectrum as well as structural formula, exact masse, GC retention times and numerous other experimental data that are relevant to the analytical toxicologist. To aid in compound identification, all substances are classified according to their toxicological categories. In addition to the mass spectral and GC data for almost 9000 substances, the two volumes contain an overview on experimental methods, plus compound indices by name and substance category.  A truly unique collection of data obtained over the course of almost three decades.  Praise for the previous editions:  "An invaluable source of reference for any environmental, toxicological or analytical laboratory." (Rapid Communications in MS)  "The excellent organization of the information facilitates their everyday use. Highly recommended." (Environmental Science and Pollution Research)  "The modern toxicological laboratory can ill afford to be without this unique work." (Veterinary Human Toxicology)

Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants and Their Metabolites

The world's most comprehensive reference for clinical and forensic toxicologists has once more been extensively updated: 2,000 data sets have been added for a total of 10,430 spectra of potentially harmful substances, including 7,800 from metabolites. In two hardbound volumes, the printed atlas contains a comprehensive listing of full reference mass spectra in order or molecular mass with the structural formula, exact mass, GC retention times and other experimental data that are relevant to the analytical toxicologist. To aid in compound identification, all substances are classified according to their toxicological categories. In addition, volume 1 contains an overview on experimental methods, plus a compound index by name. An electronic database for use with all major mass spectrometers is also available. For details, please visit www.wiley.com/go/databases.

Mass Spectral and GC Data of Drugs, Poisons, Pesticides, Pollutants, and Their Metabolites (German Edition)

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