Our bodies and body processes evolved to allow our ancestors the best chance of survival as hunter-gatherers in the Savannah. Our brains, on the other hand, have evolved intelligence, imagination, and foresight, allowing us to leave all other creatures behind, and develop complex societies, cultures, and lifestyles, far removed from those of our ancestors. The development of a modern human in utero still reflects our past, and we have created a modern, artificial world that is out of tune with our evolved bodies. Could it be that this mismatch has led to the current deadly explosion in 'lifestyle' diseases such as diabetes and obesity, and will it lead to increasingly frequent epidemics? We appear unable to evolve out of this problem, and unwilling to return to a different way of life, so how can we understand and address this increasingly crucial challenge? Gluckman and Hanson set out the case, examining issues that are at times controversial and speculative. Utilizing the latest research in epigenetics (that genes may be environmentally modified), they propose that intervention in early human development, alongside a better focus on the health of potential mothers, can make future generations better suited to the modern world.

Mismatch: Why Our World No Longer Fits Our Bodies

Gluckman, Peter

Hanson, Mark

Health, Fitness & Dieting

Oxford University Press

Explaining the practical implications of new discoveries in 'life-course biology', Nutrition and Lifestyle for Pregnancy and Breastfeeding is an informed resource on factors that affect offspring development. The impact of parental lifestyle and behavioural choices influence not only fetal development and birth outcomes, but also postnatal development, yet guidance on appropriate diet, behaviour, and exposures during pregnancy is often confusing and contradictory. With accessible explanations of the latest scientific research, and clear summaries and recommendations, this book is a valuable and authoritative guide for all levels of health care providers. The authors provide an overview of the background evidence, highlighting the importance of lifestyle choices prior to and during pregnancy. In-depth discussions of nutritional and lifestyle factors that impact on pregnancy and offspring outcomes are based on the latest research and exploration of key scientific studies. Nutrition and Lifestyle for Pregnancy and Breastfeeding is a manual offering both scientific and clinical evidence to empower health care providers and ensure they have the information necessary to confidently care for prospective and new parents.

Nutrition and Lifestyle for Pregnancy and Breastfeeding

Women's Health

Our bodies evolved to allow our ancestors the best chance of survival as hunter-gatherers in the Savannah. Our brains, on the other hand, have allowed us to develop complex societies, cultures, and lifestyles, far removed from those of our ancestors. As a result, write Peter Gluckman and Mark Hanson in Mismatch, we have created a modern, artificial world that is painfully out of tune with our evolved bodies. In a compelling narrative that begins with the Sherpa in Nepal, Gluckman and Hanson, both leading medical scientists, draw on the latest research, bringing together concepts from evolutionary biology, developmental science, medicine, anthropology and ecology to describe the nature of this mismatch, its consequences, and how we may counter it. The authors reveal that this mismatch has led to the current deadly explosion in "lifestyle" diseases such as diabetes and obesity, and it may well lead to increasingly frequent epidemics. There are broader consequences too for societies, such as the falling age of puberty, with its attendant mismatch with psychological maturity, and at the other end of life, the implications of increasing longevity. Is there any way out? Yes, say the authors. They propose that intervention in early human development, alongside a better focus on the health of potential mothers, can make future generations better suited to the modern world. In this remarkable and lucidly written book, Gluckman and Hanson identify a profound and growing problem that we ignore at our peril.

Mismatch: The Lifestyle Diseases Timebomb

Politics & Social Sciences

Anthropology

Principles of Evolutionary Medicine

Evolutionary science is critical to an understanding of integrated human biology and is increasingly recognized as a core underpinning discipline by medical and public health professionals. Advances in the fields of genomics, epigenetics, developmental biology and epidemiology have led to the growing realization that incorporating evolutionary thinking is essential for medicine to achieve its full potential. This is the first integrated and comprehensive textbook to explain the principles of evolutionary biology from a medical perspective and to focus on how medicine and public health might utilize evolutionary biology. It is written in a style which is accessible to a broad range of readers, whether or not they have had formal exposure to evolutionary science. Principles of Evolutionary Medicine is divided into three sections: the first provides a systematic approach to the principles of evolutionary biology as they apply to human health and disease, using examples specifically relevant to medicine. It incorporates chapters on evolutionary processes, molecular evolution, the evolution of humans, life history theory, and evolutionary-developmental biology. The second part illustrates the application of these principles to our understanding of nutrition and metabolism, reproduction, combatting infectious disease and stress, and human behaviour. The final section provides a general framework to show in practical terms how the principles of evolutionary medicine can be applied in medical practice and public health. This novel textbook provides the necessary toolkit for doctors and other health professionals, medical students and biomedical scientists, as well as anthropologists interested in human health, to gain a better understanding of the evolutionary processes underlying human health and disease.

Science & Math

Beedle, Alan

Biological Sciences

'Why are we losing the war against obesity and chronic disease?' This is the simple question Peter Gluckman and Mark Hanson ask, exploring the dominant myth that the exploding epidemic of obesity, heart disease, and diabetes can be tackled by focusing on adult life styles. Addressing the flawed approach of the weight-loss industry, they explain why a continued focus simply on diet and exercise will fail. Highlighting the implications of the growing burden of these problems in the developing world, they show that the scientific enterprise ignores the reality of the social, cultural, and biological determinants that make different populations and people respond differently to living in the modern nutritionally rich world. Gluckman and Hanson review the overwhelming scientific evidence that much of the problem emerges in early life and even before birth, identifying that to address these issues requires considering development in two dimensions - a life course approach and addressing the developmental challenges of countries emerging through the socioeconomic transition. Asking why the major global bodies and vested interests fail to consider these dimensions and continue with failed approaches, they conclude by discussing the complex interactions between health and the food industry, and suggest that the food industry must be co-opted as an ally in this battle, providing a clear pathway forward.

Fat, Fate, and Disease: Why exercise and diet are not enough

Exercise & Fitness

Evolutionary science is critical to an understanding of integrated human biology and is increasingly recognised as a core discipline by medical and public health professionals. Advances in the field of genomics, epigenetics, developmental biology, and epidemiology have led to the growing realisation that incorporating evolutionary thinking is essential for medicine to achieve its full potential. This revised and updated second edition of the first comprehensive textbook of evolutionary medicine explains the principles of evolutionary biology from a medical perspective and focuses on how medicine and public health might utilise evolutionary thinking. It is written to be accessible to a broad range of readers, whether or not they have had formal exposure to evolutionary science. The general structure of the second edition remains unchanged, with the initial six chapters providing a summary of the evolutionary theory relevant to understanding human health and disease, using examples specifically relevant to medicine. The second part of the book describes the application of evolutionary principles to understanding particular aspects of human medicine: in addition to updated chapters on reproduction, metabolism, and behaviour, there is an expanded chapter on our coexistence with micro-organisms and an entirely new chapter on cancer. The two parts are bridged by a chapter that details pathways by which evolutionary processes affect disease risk and symptoms, and how hypotheses in evolutionary medicine can be tested. The final two chapters of the volume are considerably expanded; they illustrate the application of evolutionary biology to medicine and public health, and consider the ethical and societal issues of an evolutionary perspective. A number of new clinical examples and historical illustrations are included. This second edition of a novel and popular textbook provides an updated resource for doctors and other health professionals, medical students and biomedical scientists, as well as anthropologists interested in human health, to gain a better understanding of the evolutionary processes underlying human health and disease.

Buklijas, Tatjana

Low, Felicia

Evolution

How do we understand and explain the apparent dichotomy between plasticity and robustness in the context of development? Can we identify these complex processes without resorting to 'either/or' solutions? Written by two leaders in the field, this is the first book to fully unravel the complexity of the subject, explaining that the epigenetic processes generating plasticity and robustness are in fact deeply intertwined. It identifies the different mechanisms that generate robustness and the various forms of plasticity, before considering the functional significance of the integrated mechanisms and how the component processes might have evolved. Finally, it highlights the ways in which epigenetic mechanisms could be instrumental in driving evolutionary change. Essential reading for biologists and psychologists interested in epigenetics and evolution, this book is also a valuable resource for biological anthropologists, sociobiologists, child psychologists and paediatricians.

Plasticity, Robustness, Development and Evolution

Bateson, Patrick

Cambridge University Press

New discoveries indicate that the most important interactions in determining our fate occur before birth. These processes are an evolutionary echo of mechanisms which allowed our ancestors to survive as hunter-gatherers. Two of the world's leading pioneering authorities reveal exciting insights into a rapidly emerging field. They suggest new ways of protecting the health of the fetus, infant and adult and cover important triggers for many emerging diseases such as obesity, diabetes and heart disease.

The Fetal Matrix: Evolution, Development and Disease

Medical Books

Basic Sciences

See the best price to sell, buy, or rent books by Gluckman, Peter. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Books by Gluckman, Peter

See the best price to sell, buy, or rent books by Gluckman, Peter. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Mismatch: Why Our World No Longer Fits Our Bodies

Nutrition and Lifestyle for Pregnancy and Breastfeeding

Mismatch: The Lifestyle Diseases Timebomb

Principles of Evolutionary Medicine

Principles of Evolutionary Medicine

Fat, Fate, and Disease: Why exercise and diet are not enough

Principles of Evolutionary Medicine

Principles of Evolutionary Medicine

Plasticity, Robustness, Development and Evolution

The Fetal Matrix: Evolution, Development and Disease