A new account of the central role developmental processes play in evolution A new scientific view of evolution is emerging--one that challenges and expands our understanding of how evolution works. Recent research demonstrates that organisms differ greatly in how effective they are at evolving. Whether and how each organism adapts and diversifies depends critically on the mechanistic details of how that organism operates--its development, physiology, and behavior. That is because the evolutionary process itself has evolved over time, and continues to evolve. The scientific understanding of evolution is evolving too, with groundbreaking new ways of explaining evolutionary change. In this book, a group of leading biologists draw on the latest findings in evolutionary genetics and evo-devo, as well as novel insights from studies of epigenetics, symbiosis, and inheritance, to examine the central role that developmental processes play in evolution. Written in an accessible style, and illustrated with fascinating examples of natural history, the book presents recent scientific discoveries that expand evolutionary biology beyond the classical view of gene transmission guided by natural selection. Without undermining the central importance of natural selection and other Darwinian foundations, new developmental insights indicate that all organisms possess their own characteristic sets of evolutionary mechanisms. The authors argue that a consideration of developmental phenomena is needed for evolutionary biologists to generate better explanations for adaptation and biodiversity. This book provides a new vision of adaptive evolution.

Evolution Evolving: The Developmental Origins of Adaptation and Biodiversity

Science & Math

Gilbert, Scott F.

Lala, Kevin N.

Feldman, Marcus

Uller, Tobias

Feiner, Nathalie

Biological Sciences

Princeton University Press

Fully updated and revised introduction to the phenomena of animal development. It provides a comprehensive account of the molecular and cellular concepts of the development while placing them in the framework of the developing embryo.

Developmental Biology

Sinauer Associates, Inc.

The Eighth Edition of Developmental Biology expands its coverage of the mechanisms of development, the roles that environmental factors play in development, the medical applications of our knowledge of development, and the roles that development plays in evolution, highlighting all the incredible advances that have been made in the last three years. Written primarily for undergraduate biology majors, it also serves to introduce graduate students and medical students to developmental biology. 
A completely updated text integrates classical developmental biology with contemporary techniques, including new material on: stem cells niches; microRNAs; sperm-egg attraction and binding; induction and maintenance of pluripotency; pioneer transcription factors and the recruitment of nucleosome remodeling proteins; left-right gene expression asymmetry; heart chamber specification; neural crest cell specification and differentiation; somite formation; human brain growth genes; the syndetome; new sources of muscle precursor cells; newly discovered mechanisms of teratogenesis; the effects of endocrine disruptors on human development; sex determination pathways in the brain; the effects of maternal nutrition on gene expression and disease susceptibility in the adult offspring; controversies over digit specification in birds and dinosaurs and whether mammalian blastomere fate is biased at the first division; and much more. Included with every copy of the book is Vade Mecum2: An Interactive Guide to Developmental Biology. In addition to a wealth of interactive content, this updated version includes a new Teachers' and Student's Resource with PowerPoint® slides of chick whole mounts and serial sections. A searchable PDF file on the CD contains full citations for the book's literature cited, with links to PubMed. The CD also includes Mary Tyler's laboratory manual, Developmental Biology: A Guide for Experimental Study, Third Edition, in electronic (PDF) format. textbook and provides more information for advanced students, historical, philosophical, and ethical perspectives on issues in developmental biology, movies, interviews, Web links, and updates. The website includes the full bibliography of literature cited in the book (over 5,000 references), most of which are linked to their PubMed citations.

Developmental Biology, Eighth Edition

Developmental Biology, Seventh Edition captures the richness, the intellectual excitement, and the wonder of contemporary developmental biology. It is written primarily for undergraduate biology majors but will be useful for introducing graduate students and medical students to developmental biology. In addition to exploring and synthesizing the organismal, cellular, and molecular aspects of animal development, the Seventh Edition expands its coverage of the medical, environmental, and evolutionary aspects of developmental biology. 
FEATURES OF THE SEVENTH EDITION 
A completely updated text integrates classical developmental biology with contemporary techniques, including the new material on vertebrate limb cell specification, microarrays, RNA interference, microtubular motors, floxed genes, vertebra formation, neural crest differentiation, neural crest specification, heart cell specification, herbicide-induced gonadal disruptions, pancreatic development, digit determination, tadpole deiodinases, insulin-like growth factors, developmental symbioses, and the developmental origins of feathers, jaws, and teeth during evolution. 
A new chapter on medical implications of developmental biology • The news is full of developmental biology and its medical implications. Therapeutic cloning and cancer therapies, in vitro fertilization, congenital anomalies, and teratogenesis are major concerns not only of scientists but of all citizens. Chapter 21, "Medical Implications of Human Development," brings these topics together and discusses: 
* the regulation of fertility * the identification of genetic defects that affect development * the identification of teratogenic compounds that affect development * the identification of factors in the maternal environment which may influence the health of the fetus or the adult * the realization that cancers can be disruptions of developmental regulation and might be cured through developmental processes * the attempts to cure developmental diseases (including cancers) through detection, cloning, stem cell therapy, and genetic engineering * the attempt to cure traumatic and degenerative disease through regeneration.

When the molecular processes of epigenetics meet the ecological processes of phenotypic plasticity, the result is a revolutionary new field: ecological developmental biology, or eco-devo. This new science studies development in the real world of predators, pathogens, competitors, symbionts, toxic compounds, temperature changes, and nutritional differences. These environmental agents can result in changes to an individual s phenotype, often implemented when signals from the environment elicit epigenetic changes in gene expression. Ecological developmental biology is a truly integrative biology, detailing the interactions between developing organisms and their environmental contexts. Ecological developmental biology also provides a systems approach to the study of pathology, integrating the studies of diabetes, cancers, obesity, and the aging syndrome into the framework of an ecologically sensitive developmental biology. It looks at examples where the environment provides expected cues for normal development and where the organism develops improperly without such cues. Data from research on teratology, endocrine disruptors, and microbial symbioses, when integrated into a developmental context, may have enormous implications for human health as well as the overall health of Earth s ecosystems. The study of epigenetics changes in gene expression that are not the result of changes in a gene s DNA sequence has recently provided startling insights not only into mechanisms of development, but also into the mechanisms and processes of evolution. The notion that epialleles (changes in chromosome structure that alter gene expression) can be induced by environmental agents and transmitted across generations has altered our notions of evolution, as have new experiments documenting the genetic fixation of environmentally induced changes in development. The widespread use of symbiosis in development provides new targets for natural selection. Ecological developmental biology integrates these new ideas into an extended evolutionary synthesis that retains and enriches the notion of evolution by natural selection.

Ecological Developmental Biology: Integrating Epigenetics, Medicine, and Evolution

Epel, David

Sinauer Associates is an imprint of Oxford University Press

During the past four years, the field of developmental biology has begun a new metamorphosis. The Ninth Edition of Developmental Biology mirrors this shift with a wholly revised text, over 600 new literature citations, and substantial reorganization of content. The introductory section has been streamlined from six chapters to three one each on developmental anatomy, the mechanisms of gene regulation during differentiation, and cell cell communication during morphogenesis. Another new feature is the addition of short part openers that address key concerns in developmental biology. These provide an introduction to the subsequent chapters, telling the reader what to expect and placing that information into a specific context. Each chapter ends with a guide to Web-based resources relevant to that chapter s content, and the Ninth Edition is the first to include a glossary of key terms. Some of the new material in this edition includes: mesenchymal and induced pluripotent stem cells; the transdifferentiation of pancreatic cells; new data on sea urchin micromere specification; the mechanisms whereby Sry and Wnt signaling determine mammalian sex; the memory of cell fate during amphibian limb regeneration; how bats got their wings and how dachshunds got their short legs.

This book captivates student interest, opening minds to the wonder of developmental biology, whilst covering required material with scientific rigour. The tenth edition reflects the exciting new age of genomics, genetic regulatory networks and digital visualization techniques while keeping focus on the major questions of animal development.

Sinauer Associates Inc.,U.S.

The only book that, in one place: - details the three main epigenetic sources of phenotype: symbionts, altered chromatin structure, and plasticity. - discusses the various ways that development can be disrupted: teratogens, endocrine disruptors, global climate change, and mismatches between diet and environment. - documents the evidence for an extended evolutionary synthesis involving the modern synthesis, evo-devo, and eco-evo-devo. The revolution in molecular technologies has created a revolution in our perception of the living world. It is life, but not as we knew it. * Symbiosis, once thought the exception to the rules of life, is now recognized as a signature of life, including its development and evolution. We function, develop, and possibly evolve as consortia. * Developmental plasticity has transformed our ways of relating the genome to both the organism and its environment, showing that the environment can instruct, as well as select, phenotypes. * Environmentally induced modifications of the genome (epialleles) can be created by ecological agents and inherited for many generations, showing the ability of environmental agents to generate selectable variation. * Disease susceptibilities--especially to diseases such as cancer, diabetes, asthma, autism, and obesity--may be inherited through epialleles caused by environmental agents, by mismatches in developmental plasticity, or by particular combinations of symbionts. * Global climate change and endocrine disruptors are affecting how organisms develop and how they behave. The science studying this new world, uncovering the relationships between genes, developing organisms, and their environments, is called ecological developmental biology. This book presents the data for ecological developmental biology, integrating it into new accounts of medicine, evolution, and embryology. The new evolutionary science created by this approach to nature is called ecological evolutionary developmental biology (eco-evo-devo). The book documents the evidence for a new, extended, evolutionary synthesis, a synthesis that: confounds the creationist belief that evolution can't be described above the species-level; integrates aging and "Western" diseases such as diabetes, atherosclerosis, cancer, and obesity into an evolutionary context; and sees interspecies interactions both within the organism and between organisms as being critical for evolution, development, and fitness. For Instructors Instructor's Resource Library This resource includes all figures (line-art illustrations and photographs) and tables from the textbook, provided as both high- and low-resolution JPEGs. All have been formatted and optimized for excellent projection quality. Also included are ready-to-use PowerPoint presentations of all figures and tables.

Ecological Developmental Biology: The Environmental Regulation of Development, Health, and Evolution

See the best price to sell, buy, or rent books by Gilbert, Scott F.. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Books by Gilbert, Scott F.

See the best price to sell, buy, or rent books by Gilbert, Scott F.. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Evolution Evolving: The Developmental Origins of Adaptation and Biodiversity

Developmental Biology

Developmental Biology, Eighth Edition

Developmental Biology

Ecological Developmental Biology: Integrating Epigenetics, Medicine, and Evolution

Developmental Biology

Developmental Biology

Developmental Biology

Developmental Biology

Ecological Developmental Biology: The Environmental Regulation of Development, Health, and Evolution