<p>Reporter genes have been used for several decades to study regulation of gene expression in vivo. However, it was little more than a decade ago that a new class of reporter genes was developed for imaging molecular events within living subjects. By following the interactions of protein molecules, researchers can resolve the complex chemical pathways that living cells utilize. This book focuses on this group of imaging reporter genes, starting with detailed descriptions of all reporter genes from different imaging modalities, including optical, MRI, and radionuclide-based imaging. Key scientists in the field explain how to enhance reporter gene imaging utility through instrumentation and the various applications of this technology. This is the first comprehensive book on all aspects of reporter gene imaging, detailing what is known in the field and future goals for research. Investigators in biomedical sciences, physicians, and the biotechnology and pharmaceutical industries will benefit from topics covered here.</p>

Molecular Imaging with Reporter Genes (Cambridge Molecular Imaging Series)

Science & Math

Gambhir, Sanjiv Sam

Yaghoubi, Shahriar S.

Biological Sciences

Cambridge University Press

<p>The field of molecular imaging of living subjects has evolved considerably and has seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: Molecular Imaging technologies , Chemistry , Molecular Imaging in Cell and Molecular Biology , Applications of Molecular Imaging , Molecular Imaging in Drug Evaluation with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.</p>

Molecular Imaging: Principles and Practice

Medical Books

Weissleder, Ralph

Ross, Brian D., Ph.D.

Rehemtulla, Alnawaz, Ph.D.

Medicine

PMPH-usa

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Books by Gambhir, Sanjiv Sam