Gastroesophageal Reflux Disease (GERD) is one of the most common maladies of mankind. Approximately 40% of the adult population of the USA suffers from significant heartburn and the numerous antacids advertised incessantly on national television represents a $8 billion per year drug market. The ability to control acid secretion with the increasingly effective acid-suppressive agents such as the H2 blockers (pepcid, zantac) and proton pump inhibitors (nexium, prevacid) has given physicians an excellent method of treating the symptoms of acid reflux. Unfortunately, this has not eradicated reflux disease. It has just changed its nature. While heartburn, ulceration and strictures have become rare, reflux-induced adenocarcinoma of the esophagus is becoming increasingly common. Adenocarcinoma of the esophagus and gastric cardia is now the most rapidly increasing cancer type in the Western world. The increasing incidence of esophageal adenocarcinoma has created an enormous interest and stimulus for research in this area. GERD brings together a vast amount of disparate literature and presents the entire pathogenesis of reflux disease in one place. In addition to providing a new concept of how gastroesophageal reflux causes cellular changes in the esophagus, GERD also offers a complete solution to a problem that has confused physicians for over a century. Both clinical and pathological information about reflux disease and its treatment are presented. GERD is meant to be used as a comprehensive reference for gastroenterologists, esophageal surgeons, and pathologists alike.

GERD: Reflux to Esophageal Adenocarcinoma

Science & Math

DeMeester, Tom R.

Chandrasoma MD, Parakrama T.

Biological Sciences

Elsevier Science

Esophageal Disease and Testing

A detailed compilation of the latest research and recommendations for the diagnosis and assessment of esophageal disorders, this reference delves into a wide range of applications and technologies currently utilized in the field including radiology, endoscopy, endoscopic ultrasonography, manometry, ambulatory manometry, pH testing, catheter-free pH testing, bilitec monitoring, and impedance plethysmography.

Medical Books

Bremner, Cedric G.

Huprich, James E.

Bremner, Ross M.

Medicine

CRC-Press

Cancer of the Esophagus

Grune Stratton

A detailed compilation of the latest research and recommendations for the diagnosis and assessment of esophageal disorders, this reference delves into a wide range of applications and technologies currently utilized in the field including radiology, endoscopy, endoscopic ultrasonography, manometry, ambulatory manometry, pH testing, catheter-free pH testing, bilitec monitoring, and impedance plethysmography.

This work focuses on the physiologic approach to the understanding and management of oesophageal disease. This is coupled with the utilization of minimally invasive thoracoscopic and laparoscopic surgery as a first option in the treatment of gastroesophageal reflux disease. oesophageal motility disorders, oesophageal diverticula, and benign oesophageal tumours. Open surgery is reserved for the initial approach to complicated oesophageal disease, reopeation of previously failed procedures, or oesophageal replacement for end-stage benign disease. This volume aims to present the current status of a changing approach to the field of oesophageal surgery.

Modern Approach to Benign Esophageal Disease: Diagnosis and Surgical Therapy

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Books by DeMeester, Tom R.