Heredity under the Microscope: Chromosomes and the Study of the Human Genome

By focusing on chromosomes, Heredity under the Microscope offers a new history of postwar human genetics. Today chromosomes are understood as macromolecular assemblies and are analyzed with a variety of molecular techniques. Yet for much of the twentieth century, researchers studied chromosomes by looking through a microscope. Unlike any other technique, chromosome analysis offered a direct glimpse of the complete human genome, opening up seemingly endless possibilities for observation and intervention. Critics, however, countered that visual evidence was not enough and pointed to the need to understand the molecular mechanisms. &nbsp; Telling this history in full for the first time, Soraya de Chadarevian argues that the often bewildering variety of observations made under the microscope were central to the study of human genetics. Making space for microscope-based practices alongside molecular approaches, de Chadarevian analyzes the close connections between genetics and an array of scientific, medical, ethical, legal, and policy concerns in the atomic age. By exploring the visual evidence provided by chromosome research in the context of postwar biology and medicine, Heredity under the Microscope sheds new light on the cultural history of the human genome.

History

de Chadarevian, Soraya

Americas

University of Chicago Press

By focusing on chromosomes, Heredity under the Microscope offers a new history of postwar human genetics. Today chromosomes are understood as macromolecular assemblies and are analyzed with a variety of molecular techniques. Yet for much of the twentieth century, researchers studied chromosomes by looking through a microscope. Unlike any other technique, chromosome analysis offered a direct glimpse of the complete human genome, opening up seemingly endless possibilities for observation and intervention. Critics, however, countered that visual evidence was not enough and pointed to the need to understand the molecular mechanisms. &nbsp; Telling this history in full for the first time, Soraya de Chadarevian argues that the often bewildering variety of observations made under the microscope were central to the study of human genetics. Making space for microscope-based practices alongside molecular approaches, de Chadarevian analyzes the close connections between genetics and an array of scientific, medical, ethical, legal, and policy concerns in the atomic age. By exploring the visual evidence provided by chromosome research in the context of postwar biology and medicine, Heredity under the Microscope sheds new light on the cultural history of the human genome.

Models: The Third Dimension of Science (Writing Science)

Now that ‘3-D models’ are so often digital displays on flat screens, it is timely to look back at the solid models that were once the third dimension of science. This book is about wooden ships and plastic molecules, wax bodies and a perspex economy, monuments in cork and mathematics in plaster, casts of diseases, habitat dioramas, and extinct monsters rebuilt in bricks and mortar. These remarkable artefacts were fixtures of laboratories and lecture halls, studios and workshops, dockyards and museums. Considering such objects together for the first time, this interdisciplinary volume demonstrates how, in research as well as in teaching, 3-D models played major roles in making knowledge. Accessible and original chapters by leading scholars highlight the special properties of models, explore the interplay between representation in two dimensions and three, and investigate the shift to modelling with computers. The book is fascinating reading for anyone interested in the sciences, medicine, and technology, and in collections and museums.

Science & Math

Evans, Christopher

Jordanova, Ludmilla

Hopwood, Nick

Baker, Malcolm

Boumans, Marcel

Francoeur, Eric

Griesemer, James

Mazzolini, Renato G.

Mehrtens, Herbert

Research

Stanford University Press

Nick Hopwood

Earth Sciences

See the best price to sell, buy, or rent books by de Chadarevian, Soraya. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Books by de Chadarevian, Soraya