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The Arrow of Time: The Quest to Solve Time's Greatest Mystery

Science & Math

HIGHFIELD, Roger

Coveney, Peter

Physics

Flamingo

By the end of the twenty-first century, computer-based modelling and simulation will be integral to the way clinical decisions are taken. Drugs will be selected on the basis of an individual patient's "digital profile", while clinical treatments will be tailor-made for the individual in question. For this to come to pass, however, we must prepare for a future where we can simulate our own bodies with precision, drawing upon remarkable advances in information technology, computer, mathematical, physical and engineering science, data management, and high performance computing. Computational Biomedicine lays the foundations for a new approach to the subject - one that unifies the different strands of a broad-ranging subject, and demonstrates how computational biomedicine is a powerful tool with the potential to revolutionise our understanding of the human body, and the therapeutic strategies available to maintain and protect it. Written by a team of world-leading experts in the field, it explores the modelling of physiological systems at different scales - cells, tissues, organs - before considering the issues around biomedical computing, and data collection and analysis. It emphasises how a theoretical understanding of computational biomedicine translates into practice, with illustrative examples and case studies used throughout. Computational Biomedicine is the perfect introduction to the subject for anyone new to the field, from student to researcher. Online Resource Centre The Online Resource Centre to accompany Computational Biomedicine features figures from the book in electronic format, for download by registered adopters.

Computational Biomedicine

Hunter, Peter

Díaz, Vanessa

Viceconti, Marco

Biological Sciences

Oxford University Press

The Arrow of Time

Random House Value Publishing

The visionary science behind the digital human twins that will enhance our health and our future\nVirtual You is a panoramic account of efforts by scientists around the world to build digital twins of human beings, from cells and tissues to organs and whole bodies. These virtual copies will usher in a new era of personalized medicine, one in which your digital twin can help predict your risk of disease, participate in virtual drug trials, shed light on the diet and lifestyle changes that are best for you, and help identify therapies to enhance your well-being and extend your lifespan―but thorny challenges remain.\nIn this deeply illuminating book, Peter Coveney and Roger Highfield reveal what it will take to build a virtual, functional copy of a person in five steps. Along the way, they take you on a fantastic voyage through the complexity of the human body, describing the latest scientific and technological advances―from multiscale modeling to extraordinary new forms of computing―that will make “virtual you” a reality, while also considering the ethical questions inherent to realizing truly predictive medicine.\nWith an incisive foreword by Nobel Prize–winning biologist Venki Ramakrishnan, Virtual You is science at its most astounding, showing how our virtual twins and even whole populations of virtual humans promise to transform our health and our lives in the coming decades.

Virtual You: How Building Your Digital Twin Will Revolutionize Medicine and Change Your Life

Computers & Technology

Computer Science

Princeton University Press

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Books by Coveney, Peter