A unique exploration of the principles and methods underlying the Human Genome Project and modern molecular genetics and biotechnology-from two top researchers In Genomics, Charles R. Cantor, former director of the Human Genome Project, and Cassandra L. Smith give the first integral overview of the strategies and technologies behind the Human Genome Project and the field of molecular genetics and biotechnology. Written with a range of readers in mind-from chemists and biologists to computer scientists and engineers-the book begins with a review of the basic properties of DNA and the chromosomes that package it in cells. The authors describe the three main techniques used in DNA analysis-hybridization, polymerase chain reaction, and electrophoresis-and present a complete exploration of DNA mapping in its many different forms. By explaining both the theoretical principles and practical foundations of modern molecular genetics to a wide audience, the book brings the scientific community closer to the ultimate goal of understanding the biological function of DNA. Genomics features: * Topical organization within chapters for easy reference * A discussion of the developing methods of sequencing, such as sequencing by hybridization (SBH) in which data is read through words instead of letters * Detailed explanations and critical evaluations of the many different types of DNA maps that can be generated-including cytogenic and restriction maps as well as interspecies cell hybrids * Informed predictions for the future of DNA sequencing

Genomics: The Science and Technology Behind the Human Genome Project

Science & Math

Cantor, Charles R.

Smith, Cassandra L.

Biological Sciences

Wiley-Interscience

Biophysical Chemistry, Part 1: The Conformation of Biological Macromecules

W.H.Freeman & Co.

One of a three-part series, Biophysical Chemistry: Part I: The Conformation of Biological Macromolecules combines with two other volumes to create the definitive text on the physical properties of biological macromolecules and the physical techniques used to study them.

Biophysical Chemistry: Part I: The Conformation of Biological Macromolecules

Schimmel, Paul R.

W.H.Freeman

Three-part series remains the definitive text on the physical properties of biological macromolecules and the physical techniques used to study them. It is appropriate for a broad spectrum of advanced undergraduate and graduate courses and serves as a comprehensive reference for researchers. Part I: The Conformation of Biological Macromolecules 1980, paper, 365 pages, 158 illustrations 0-7167-1188-5 Part II: Techniques for the Study of Biological Structure and Function 1980, paper, 365 pages, 158 illustrations 0-7167-1190-7 Part III: The Behavior of Biological Macromolecules 1980, paper, 597 pages, 243 illustrations 0-7167-1192-3

Biophysical Chemistry: Techniques for the Study of Biological Structure and Function

Biophysical Chemistry, Part 2: Techniques for the Study of Biological Structure and Function

W.H.Freeman and Company

Three-part series remains the definitive text on the physical properties of biological macromolecules and the physical techniques used to study them. It is appropriate for a broad spectrum of advanced undergraduate and graduate courses and serves as a comprehensive reference for researchers. Part I: The Conformation of Biological Macromolecules 1980, paper, 365 pages, 158 illustrations 0-7167-1188-5 Part II: Techniques for the Study of Biological Structure and Function 1980, paper, 365 pages, 158 illustrations 0-7167-1190-7 Part III: The Behavior of Biological Macromolecules 1980, paper, 597 pages, 243 illustrations 0-7167-1192-3

Biophysical Chemistry, Part 3: The Behavior of Biological Macromolecules

W.H.Freeman & Co Ltd

One of a three-part series, Biophysical Chemistry: Part III: The Behavior of Biological Macromolecules combines with two other volumes to create the definitive text on the physical properties of biological macromolecules and the physical techniques used to study them.

Biophysical Chemistry: Part III: The Behavior of Biological Macromolecules

Annual Review of Biophysics and Biomolecular Structure: 1994 (Annual Review of Biophysics & Biomolecular Structure)

Stroud, Robert M.

Annual Reviews

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Books by Cantor, Charles R.