Designing Clinical Research has been extensively revised and continues to set the standard as a practical guide for doctors, nurses, pharmacists, and other health professionals involved in all forms of clinical, translational, and public health research. It presents advanced epidemiologic concepts in a reader-friendly way, and suggests common sense approaches to the challenging judgments involved in designing, funding, and implementing. New to this edition:
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<li>Expanded and updated content in every chapter, with new material on: • non-inferiority trials for comparative effectiveness research • incidence-density case-control studies • confounding and effect modification • diagnostic test studies to inform prediction rules • ethical aspects of whole genome sequencing • automated data management approaches • new NIH grant-writing requirements</li>Color format, and Electronic access, powered by Inkling™ as a free companion to the text • viewable through your browser or as a download to tablet or smartphone • the complete text with optimized navigation • note-sharing, highlighting and bookmarking capability • cross-linking of references and content • rapid search options linked to the new glossary</ul>

Designing Clinical Research

Medical Books

Browner MD MPH, Warren S

Newman MD MPH, Thomas B

Hulley MD MPH, Dr. Stephen B

Cummings MD, Steven R.

Grady MD MPH, Deborah G.

Administration & Medicine Economics

For more than 30 years, Designing Clinical Research has set the standard as the most practical, authoritative guide for physicians, nurses, pharmacists, and other practitioners involved in all forms of clinical and public health research. Using a reader-friendly writing style, Drs. Warren S. Browner, Thomas B. Newman, Steven R. Cummings, Deborah G. Grady, Alison J. Huang, Alka M. Kanaya, and Mark J. Pletcher, all of the University of California, San Francisco, provide up-to-date, commonsense approaches to the challenging judgments involved in designing, funding, and implementing a study. This state-of-the-art fifth edition features new figures, tables, and design, as well as new editors, new content, and extensively updated references to keep you current. <ul> <li> Covers clinical research in its many forms, including clinical trials, observational studies, translational science, and patient-oriented research. </li> <li> Presents epidemiologic terms and principles and advanced conceptual material in a practical and reader-friendly manner. </li> <li> Discusses key changes in the field, including confounding and directed acyclic graphs, surrogate outcomes and biomarkers, instrumental variables and Mendelian randomization, regression discontinuity designs, alternative data sources, AI and machine learning, pilot studies, as well as an update on P values and Bayesian analysis.. </li> <li> Covers modifications of classic randomized trials, such as pre/post, interrupted time series, difference-in-differences, stepped wedge and cluster randomized designs, as well as randomized trials in health systems. </li> <li> Adds new chapters on qualitative approaches to clinical research and on community-engaged research &nbsp; Enrich Your eBook Reading Experience </li> <li> Read directly on your preferred device(s),such as computer, tablet, or smartphone </li> <li> Easily convert to audiobook,powering your content with natural language text-to-speech </li> </ul>

Science & Math

Huang, Alison J

KANAYA, ALKA M.

PLETCHER, MARK J

Biological Sciences

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Books by Browner MD MPH, Warren S