Medical innovation as it stands today is fundamentally unsustainable. There is a widening gap between what biomedical research promises and the impact that it is currently achieving, in terms of patient benefit and health system improvement. This book highlights the global problem of the ineffective translation of bioscience innovation into health system improvements and its consequences, analyses the underlying causative factors and provides powerful prescriptions for change to close the gap. It contrasts the progress in biomedicine with other areas of scientific and technological endeavour, such as information technology, in which there are faster and more reliable returns for society from scientific advance. It asks searching questions about whether society is right to expect so much from biomedicine and why we have become accustomed to such poor returns. Throughout the book, techniques such as stratified medicine, open innovation, adaptive development and personalised adherence are discussed and described in terms accessible to the non-specialist, and their impact on the innovation gap explored. By using examples in which bottlenecks have prevented progress, such as dementia and antibiotic-resistant infections, and in which these barriers have been overcome, such as HIV treatment, Bioscience - Lost in Translation? lays out a strategy for advancing the innovation process, presenting suggestions for how health systems can move from being passive recipients of innovation to being active participants in development.

Bioscience - Lost in Translation?: How precision medicine closes the innovation gap

Medical Books

Barker, Richard

Administration & Medicine Economics

Oxford University Press

Over the last couple of years, the credit crunch has driven a near-collapse of the world's financial systems. With the benefit of hindsight, many say this could have been predicted and avoided. Over the next 10-20 years, healthcare is headed for its own meltdown: an inability to fund the growth in demand and the appearance of costly new medical technology within the current healthcare systems framework. This 'meltdown' will not be as sudden as that in the world of finance: it will occur over the next 20 years, but the failure of the current sources of healthcare funding to meet our expectations of care quantity and quality will have consequences every bit as serious as the banking crisis. The warning signs are there, the crisis is already being predicted - but is it inevitable, or can it be avoided? This book offers a penetrating analysis of the underlying problems, and offers some simple, but far-reaching solutions to bring supply and demand back into balance and avoid the meltdown. It is not a contribution to the current political debate but a primer for the changes to the underlying fabric of healthcare if reforms such as "Obamacare" have any chance of sustainable success. In the course of the book, we confront many topical challenges: How can people be persuaded to manage their own health better?; Can we afford to spend more of today's money on disease prevention and detection, to save future costs?; Will 'personalised medicine' be cheaper, or more expensive?; Are healthcare IT systems a key part of the solution or doomed to be expensive white elephants?; and most importantly: What will the future of healthcare look like, for us and for our children and grandchildren? To bring the answers to this final question alive, the book uses a fictitious family, the Carters, to illustrate the changes we will see, the dilemmas we will face and the solutions we must strive for. Interspersed between the text are the vignettes of members of the family, their diseases and treatments and how change has affected each of their lives.

2030 - The Future of Medicine: Avoiding a Medical Meltdown

About Case Method: Tasks and Deliverables Analysts, project leaders and system developers can now build integrated business systems by using this complete guide to ORACLE's CASE Method. This highly practical book identifies the key tasks and defines the major deliverables required at every stage of the development life cycle. Highlights of the book include: *clear checklists, estimating factors and quality controls for application system development *helpful guidelines for reviewing user specifications, and choosing how and when to use prototyping *comprehensive documentation forms for strategic planning through implementation. It is designed to be equally valuable as a training aid and as a 'hot- line' reference to ensure high-quality deliverables that meet the requirements of users.

Case*Method: Tasks and Deliverables

Computers & Technology

Computer Science

Addison-Wesley

This definitive book is endorsed by ORACLE, one of the leading database corporations today, and explains key techniques for defining the functionality of a business and subsequent high-quality integrated systems.

Case*Method: Function and Process Modelling

Longman, Cliff

Databases & Big Data

Structured software development methods such as CASE Method offer significant productivity gains for business applications, dramatically improving the likelihood of getting it right the first time and reducing the risk of projects running over time and budget. More recently, iterative methods have been introduced with the aim of using rapid prototyping to speed the development process further for suitable projects. As CASE Method Fast-track: A RAD Approach reveals, the key to success is 'light but tight' project management. It shows how project management techniques must evolve to match the evolution of fast-track development methods, whilst emphasizing the importance of user involvement and training, the evolutionary approach to documentation, and the acceleration and quality that can be provided by CASE tools. CASE Method Fast-track: A RAD Approach provides a highly practical guide to using rapid prototyping techniques within the CASE Method framework.

Case Method Fast-Track: A Rad Approach (Computer Aided System Engineering)

Clegg, Dai

Business & Money

This book is about the methods used to value companies. Valuation methods such as the price-earnings ratio, dividend yeild and EVA are found frequently in stockbrokers' reports and in the financial press. There has also been an explosion of interest in 'shareholder value' in recent years, with a corresponding need to understand how value is created and measured. Determining Value contains both the analytical review of valuation models and also evaluation of the data available for use in valuation models. This information is not at present available together in one textbook and has not been academically and critically evaluated.

Determining Value: Valuation Models and Financial Statements

Finance

Addison-Wesley Longman Ltd

Reviewed by Nokia's subject matter experts, the authors cover the entire development process - from design, programming, and testing to debugging and deployment - while providing sixty projects, each with full C++ source code and installation scripts. This is a guide to Series 60 development for C++ programmers and software designers.

Developing Series 60 Applications: A Guide for Symbian C++ Developers

Edwards, Leigh

Emcc Software Ltd

Networking & Cloud Computing

Addison-Wesley Professional

The inside scoop on a leading-edge data storage technology The rapid growth of e-commerce and the need to have all kinds of applications operating at top speed at the same time, all on a 24/7 basis while connected to the Internet, is overwhelming traditional data storage methods. The solution? Storage Area Networks (SANs)--the data communications technology that's expected to revolutionize distributed computing. Written by top technology experts at VERITAS Software Global Corporation, this book takes readers through all facets of storage networking, explaining how a SAN can help consolidate conventional server storage onto networks, how it makes applications highly available no matter how much data is being stored, and how this in turn makes data access and management faster and easier. System and network managers considering storage networking for their enterprises, as well as application developers and IT staff, will find invaluable advice on the design and deployment of the technology and how it works. Detailed, up-to-date coverage includes: <ul>
<li>The evolution of the technology and what is expected from SANs</li> <li>Killer applications for SANs</li> <li>Full coverage of storage networking and what it means for the enterprise's information processing architecture</li> <li>Individual chapters devoted to the storage, network, and software components of storage networking</li> <li>Issues for implementation and adoption</li> </ul>

Storage Area Network Essentials

Certification

John Wiley&Sons

An introduction to the fundamentals of accounting and how it is used that will help students apply accounting as a usable, everyday business tool. It adopts an intuitive, informal approach to describe basic principles - what they are, why they exist and how they are used - to help students see the connections between different parts of accounting and the rest of the business world. Written by an award-winning teacher and former management accountant, it encourages students to engage with the material by using questions and worked examples to test knowledge and understanding as they read. It includes a glossary of financial terms that is a useful guide to the language of business. Part of the Cambridge Short Introductions series of concise, authoritative guides to core subjects in business and management.

Short Introduction to Accounting Euro Edition (Cambridge Short Introductions to Management)

Cambridge University Press

With 36 netsuke in colour and 850 monochrome illustrations.

Netsuke. The Miniature Sculpture of Japan

Crafts, Hobbies & Home

Smith, Lawrence

Crafts & Hobbies

British Museum Publications Limited

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Books by Barker, Richard