Toxicological Evaluation of Veterinary Drug Residues in Food (43)

Evaluates the design and findings of studies relevant to the safety assessment of selected veterinary drug residues in food. The book which is part of a long-running series prepared by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) gives toxicologists the food industry and regulatory agencies a record of the scientific evidence considered when the Committee allocates or revises acceptable daily intakes and other endpoints. Emphasis is placed on studies that relate specific exposure levels to specific toxic effects or guide the meaningful extrapolation of animal data to the human condition. Through its careful attention to questions of study design methodology and the validity of reported data the book also demonstrates the strict safety standards used by JECFA in its efforts to protect consumers from any possible toxicological or pharmacological hazard linked to the consumption of veterinary drug residues. Separate toxicological monographs are presented for one b-adrenoceptor blocking agent (carazolol) one antimicrobial agent (thiamphenicol) one insecticide (phoxim) and four production aids (estradiol-17b progesterone testosterone and porcine somatotropin).