Rheumatology (Therapeutic Strategies)

Therapeutic Strategies in Rheumatic Disorders offers a global perspective on current approaches to diagnosis and therapy for musculoskeletal and joint disease, reporting on the latest clinical trials and 'breaking news' that will have an impact on future treatment strategies. Recent trial data has shown that early inflammatory arthritis responds well to prompt, aggressive treatment with biologics and combination therapy. In addition to anti-TNF, newer biological agents are now emerging that block other mediators of inflammation and damage, and continuing advances in pharmacogenetics permit individually tailored therapeutic regimes that balance efficacy and toxicity. In osteoporosis, a bewildering array of therapeutic options are available - the challenge for the clinician is deciding on which is appropriate for each patient. Progress is also being made in understanding and treating the numerous complications concomitant with rheumatic disease, particularly pulmonary hypertension. The increasing evidence that NSAIDs and COX-2 inhibitors carry attendant risks and should be used with care presents a further example of how the clinician must stay abreast of latest developments. In this book, experts in each of these fields guide the reader through the many options now available to clinicians combating these diseases, providing a clear account of current best practice and possible future developments.