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Genomic Disorders: The Genomic Basis of Disease

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Genomic Disorders: The Genomic Basis of Disease image
ISBN-10:

1617376426

ISBN-13:

9781617376429

Edition: Softcover reprint of hardcover 1st ed. 2006
Released: Dec 09, 2010
Publisher: Humana
Format: Paperback, 444 pages
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Description:

A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.

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