General surgical pathology and therapeutics; in fifty lectures. A text-book for students and physicians

This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1871 Excerpt: ...to tissue, as seems most probable, there is no reason for not referring to them the formation of pus in the thrombus, just as we do to the white cells wandering out of the vessels, for the coagulation of the blood is not firm enough to entirely prevent cell-movement. That the thrombus may change to true pus by division of the white blood-cells does not appear to me disproved; we have already mentioned that this pus, which is usually encapsulated, does not enter the circulation, or does so very rarely, and hence has no direct connection with pyaemia. To resume my experiences of venous thrombi, and the history of thrombus, they are to the effect that most venous thrombi are the result of very acute inflammation of cellular tissue, (especially under fasciae, or tense skin, and in bone), and that the coagulum undergoes the same metamorphoses as the inflammatory new formation. If the latter lead to formation of tissue, the thrombi are also organized to connective tissue; if the inflammation goes on to suppuration or putrefaction, the thrombi also suppurate or putrefy and break down. This is the easier to understand, as we know, from Von Recklinghausen's and BubnojjTs investigations, that the cells from the tissue may pass through the walls of the vein into the thrombus. The walls of the vein have the same fate as the thrombus and surrounding tissue: they are infiltrated with plastic matter, and become thicker, or they suppurate. Thrombus, with phlebitis, may also run its course as a purely local disease, as not unfrequently happens after venesection, and in some other cases. Then there can only be further danger when the thrombus is friable, or when there is purulent or putrid destruction of the coagulum. The central end of the thrombus (as we stated when speaki...