Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales Promelas)

Within the last decade, attention has focused upon predictive toxicology for screening chemicals regarding their potential hazard to the environment. Due to the value of using structure-activity relationships to estimate aquatic toxicity, strong needs have developed for consistent and accurate data bases. Volumes 1 through 5 of the ACUTE TOXICITIES OF ORGANIC CHEMICALS TO FATHEAD MINNOWS (PIMEPHALES PROMELAS) contain original data from 779 acute toxicity tests using 653 different chemicals and encompass 12 years of effort. All the toxicity tests were perfomed in water of uniform chemical characteristics and with a single test species. Additional information provided includes: test chemical name and commercial source; molecular formula and weight; chemical purity; method of chemical analysis and measured concentrations for each treatment; test temperature; dissolved oxygen, hardness, alkalinity and pH values for all treatments, plus the control; length, weight and loading factors for test organisms; 96-hr mortality (LC50) and effect (EC50) values; graphical depictions of the mortality and effect data in relationship to duration of exposure. Detailed behavioral observations of the test organisms during the exposures were recorded for most tests. Volume 5 contains cumulative indices to contents of volumes 1-5 which are arranged alphabetically and according to chemical formula.