Hematology

"Prepared as a syllabus for the course in cell biology for Harvard medical students, this is a superb, up-to-date digest, with emphasis on the pathophysiology of hematological disorders. Pertinent clinical features with recommended diagnostic procedures are recommended.... Therapy is accurately covered in general but not specific terms. The book is highly recommended." —American Scientist The general organization of the syllabus remains as before—red cells are treated, then white cells, then clotting—and the outline format has been retained. As before, the lectures provide an intensive survey of the biology, physiology, and pathophysiology of blood and the blood-forming organs with systematic consideration of hematopoiesis, the "formed element," blood groups, immunoglobulins and other plasma proteins, and blood coagulation. Within this framework, however, much of the material has been radically revised and augmented. The most extensive revisions cover vitamin B12 deficiency, thalassemias, hemolytic anemias associated with membrane disorders, pathology of malignant lymphomas, platelets, and the newer aspects of protein interactions in blood coagulation. Recent advances in molecular biology as it pertains to hematology research are also referenced. The contributors are Chester A. Alper, William S. Beck, H. Franklin Bunn, William B. Castle, Allen C. Crocker, Robert I. Handin, James H. Jandl, Samuel E. Lux, John C. Long, David G. Nathan, Stephen H. Robinson, Robert D. Rosenberg, David S. Rosenthal, Geoffrey K. Sherwood, Thomas P. Stossel, and John T. Truman.