ODE/PDE α-synuclein Models for Parkinson’s Disease

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ODE/PDE α-synuclein Models for Parkinson’s Disease image
ISBN-10:

0128146141

ISBN-13:

9780128146149

Edition: 1
Released: Feb 28, 2018
Publisher: Academic Press
Format: Paperback, 228 pages

Description:

ODE/PDE Alpha-Synuclein Models for Parkinson’s Disease discusses a mechanism for the evolution of Parkinson’s Disease (PD) based on the dynamics of the protein α-synuclein, a monomer that has been implicated in this disease. Specifically, α-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the α-synuclein monomer and polymer, and then details the methodology for the numerical integration of ODE/PDE systems which can be applied to computer-based analyses of alternative models based on the reader's interest.

This book facilitates immediate computer use for research without the necessity to first learn the basic concepts of numerical analysis for ODE/PDEs and programming algorithms

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