Human cloning has grabbed people's imagination, but that is merely a diversion--and one we personally regret and find distasteful. We did not make Dolly for that ... Our work completes the biotechnological trio: genetic engineering, genomics, cloning. It also provides an extraordinarily powerful scientific model for studying the interactions of the genes and their surroundings--interactions that account for so much of development and disease. Taken together, the new biotechnologies and the pending scientific insights will be immensely powerful. Truly they will take humanity into the age of biological control. 
The cloning of Dolly in 1996 from the cell of an adult sheep was a pivotal moment in history. For the first time, a team of scientists, Led by Ian Wilmut and Keith Campbell at the Roslin Institute near Edinburgh, was able to clone a whole mammal using a single cultured adult body cell, a breakthrough that revolutionized three technologies and brought science ever closer to the possibility of human cloning. 
In this definitive account, the scientists who accomplished this stunning feat explain their hypotheses and experiments, their conclusions, and the implications of their work. Researchers have already incorporated into sheep the gene for human factor IX, a blood-clotting protein used to treat hemophilia. In the future, cultures of mammary cells may prove to be valuable donor material, and genetically modified animal organs may be transplanted into humans. Normal pig organs, for example, are rapidly destroyed by the human immune system, but if altered genetically, they could alleviate the serious shortage of available organs. Genetically engineered sheep are also expected to be valuable as models for genetic defects that mimic human disorders such as cystic fibrosis, and for cell-based therapies for diseases--such as Parkinson's, diabetes, and muscular dystrophy--that lack universally dependable treatments. 
But what are the ethical issues raised by this pioneering research, and how are we to reconcile them with the enormous possibilities? Written with award-winning science writer Colin Tudge, The Second Creation is a Landmark work that details the most exciting and challenging scientific discovery of the twentieth century--with the furthest-reaching ramifications for the twenty-first.

The Second Creation: Dolly and the Age of Biological Control

Science & Math

Tudge, Colin

Wilmut, Ian

Campbell, Keith

Evolution

Farrar. Straus & Giroux

A brave, moral argument for cloning and its power to fight disease. A timely investigation into the ethics, history, and potential of human cloning from Professor Ian Wilmut, who shocked scientists, ethicists, and the public in 1997 when his team unveiled Dolly—that very special sheep who was cloned from a mammary cell. With award-winning science journalist Roger Highfield, Wilmut explains how Dolly launched a medical revolution in which cloning is now used to make stem cells that promise effective treatments for many major illnesses. Dolly's birth also unleashed an avalanche of speculation about the eventuality of cloning babies, which Wilmut strongly opposes. However, he does believe that scientists should one day be allowed to combine the cloning of human embryos with genetic modification to free families from serious hereditary disease. In effect, he is proposing the creation of genetically altered humans. 20 illustrations.

After Dolly: The Uses and Misuses of Human Cloning

HIGHFIELD, Roger

Health, Fitness & Dieting

W.W.Norton

A brave, moral argument for cloning and its power to fight disease. A timely investigation into the ethics, history, and potential of human cloning from Professor Ian Wilmut, who shocked scientists, ethicists, and the public in 1997 when his team unveiled Dolly―that very special sheep who was cloned from a mammary cell. With award-winning science journalist Roger Highfield, Wilmut explains how Dolly launched a medical revolution in which cloning is now used to make stem cells that promise effective treatments for many major illnesses. Dolly's birth also unleashed an avalanche of speculation about the eventuality of cloning babies, which Wilmut strongly opposes. However, he does believe that scientists should one day be allowed to combine the cloning of human embryos with genetic modification to free families from serious hereditary disease. In effect, he is proposing the creation of genetically altered humans. 20 illustrations

After Dolly: The Promise and Perils of Cloning

Biological Sciences

W.W.Norton&Company

This new addition to the Veterinary Health Series provides comprehensive and up-to-date coverage of breeding and fertility in animals from both temperate and tropical environments. Taking a practical, problem-oriented approach to the theory and practice of animal breeding and infertility, it deals systematically with the typical approaches and problems encountered in the treatment of cattle, goats, horses, pigs and sheep in individual chapters, written by professionals in the field

Animal Breeding and Infertility

Medical Books

Meredith, M.

POWELL, Don

Pidduck, Heather, G.

Long, Susan, E.

Dobson, Hilary

Hartigan, Patrick, J.

Bretzlaff, Katherine

Stoneham, Sarah, J.

Williams, Huw, Ll.

Veterinary Medicine

Wiley/Blackwell

The cloning of Dolly in 1996 from the cell of an adult sheep was a pivotal moment in history. For the first time, a team of scientists, led by Ian Wilmut and Keith Campbell, was able to clone a whole mammal using a single cultured adult body cell, a breakthrough that revolutionized three technologies--genetic engineering, genomics, and cloning by nuclear transfer from adult cells—and brought science ever closer to the possibility of human cloning. In this definitive account, the scientists who accomplished this stunning feat explain their hypotheses and experiments, their conclusions, and the ethical and scientific ramifications of their work. Written with award-winning science writer Colin Tudge, The Second Creation is a landmark work that details the most exciting and challenging scientific discovery of the twentieth century.

Harvard University Press

Recounts how Dolly the clone sheep was created and covers the techniques for her predecessors, Megan and Morag, who were cloned from embryo cells. The authors explain the scientific reasons behind their research, discuss where they believe this technology will lead, and address the ethical issues that have been raised by Dolly's creation.

Second Creation: The Age of Biological Control by the Scientists Who Cloned Dolly

Headline Book Pub Ltd

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Books by Wilmut, Ian