<p>This volume explores the myriad of techniques and methodological approaches that are being used in breast cancer research. The authors critically evaluate of the advantages and disadvantages of current methodologies, starting with the tools available for understanding the architecture of the human breast, including its tissue and cellular composition. The volume discusses the importance of functional studies in breast cancer research, especially with the help of laser capture microdissection, which allows the separation of small amounts of tissue, as well as specific cells, for biochemical analysis. In addition, the authors address methodologies including stem cell separation, which has helped in significantly understanding their role in normal breast development, but also further the understanding of breast cancer and its therapeutic management. The use of in vitro techniques and established cell lines for mechanistic studies in chemotherapeutic approaches have been invaluable will be discussed. Imaging techniques for evaluating in vitro and in vivo behavior of normal and cancerous breast tissue will be explored, as it provides a better understanding of the physiopathology of cancer. The volume will also discuss the molecular analysis of gene function in breast cancer through the transcriptomic and epigenomic profile. More importantly, the advancement of more refined techniques in sequencing will be covered. This monograph will be a comprehensive, authoritative and timely, as it addresses the emerging approaches used in breast cancer research.</p>

Techniques and Methodological Approaches in Breast Cancer Research

Health, Fitness & Dieting

RUSSO, JOSE

Russo, Irma H.

Diseases & Physical Ailments

Springer

<p>This richly-illustrated atlas-like book provides a foundation for the biological and molecular understanding of how the mammary gland develops and how breast cancer originates. The main goal is to comprehensively review in ten chapters fundamental knowledge in breast cancer. New paradigms are described in which induction of differentiation in the mammary gland can promote prevention and cure of breast cancer. The text is extremely helpful both for clinicians treating patients and researchers looking for new avenues of development.</p>

Molecular Basis of Breast Cancer: Prevention and Treatment

See the best price to sell, buy, or rent books by Russo, Irma H.. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Books by Russo, Irma H.

See the best price to sell, buy, or rent books by Russo, Irma H.. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Techniques and Methodological Approaches in Breast Cancer Research

Techniques and Methodological Approaches in Breast Cancer Research

Molecular Basis of Breast Cancer: Prevention and Treatment